PMID: 9005887Jan 1, 1997Paper

Implication of the negative U wave during dobutamine stress echocardiography

Journal of Electrocardiology
Y MiuraA Kuroiwa

Abstract

Although the development of negative U waves during exercise is a highly specific marker for detecting coronary artery disease, their assessment during exercise is difficult. The clinical significance of the negative U wave during dobutamine stress echocardiography was investigated in 181 patients who had suspected coronary artery disease. Dobutamine-induced negative U waves appeared in 28 patients (16%) during dobutamine infusion. Coronary angiography showed coronary artery disease in 114 of the 181 patients. The sensitivity and specificity of the negative U wave for detecting coronary artery disease were 22 and 96%, respectively, while the corresponding values for ischemic ST-T changes were 49 and 76%, respectively. The negative U wave appeared during low-dose infusion of dobutamine (5-10 microg/kg/min) in 82% of the patients with this wave. In the 21 patients who had both a negative U wave and an inducible regional wall motion abnormality during dobutamine infusion, the development of the negative U wave was either simultaneous with or earlier than that of the wall motion abnormality. Although its sensitivity was low, the negative U wave during dobutamine stress echocardiography is a highly specific marker for detecting coro...Continue Reading

References

May 1, 1992·Journal of the American College of Cardiology·D S SegarH Feigenbaum
Jun 1, 1982·The American Journal of Cardiology·H KishidaB Surawicz
Oct 1, 1983·British Heart Journal·K MiwaC Kawai
Nov 1, 1993·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·M TakeuchiA Kuroiwa
Sep 1, 1995·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·M TakeuchiA Kuroiwa
Jan 1, 1957·Circulation·C PAPP

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Citations

Jun 6, 2012·BMJ Case Reports·Shelley RaveendranNadim Malik
Nov 22, 2001·American Heart Journal·C KimR Redberg

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