PMID: 11927313Apr 3, 2002Paper

Implications of radioactive seed migration to the lungs after prostate brachytherapy

Urology
Murali K AnkemRobert E Weiss

Abstract

To review the incidence and the impact of pulmonary seed migration after prostate brachytherapy on lung function. Isolated reports of seed migration to the lungs after prostate brachytherapy have been published; however, the clinical consequences of this pulmonary migration have not been adequately evaluated. We performed a retrospective review of patients undergoing prostate brachytherapy from 1998 to 2000. Pulmonary imaging with chest x-ray was performed 15 to 90 days (median 45) after the procedure. The chest radiographs were reviewed by a single radiologist (V.S.D.), and patients with seed migration to the lungs were evaluated by a single pulmonologist (A.M.H.) using a questionnaire, chest radiography, and pulmonary function tests. Computed tomography of the prostate after seed implantation was performed to check seed position and dosimetry. Odds ratio, confidence intervals, chi-square tests, and logistic regression analysis were performed to evaluate the relationship between the type and number of seeds used, the incidence of pulmonary migration, and the effects on pulmonary function. A total of 83 patients underwent prostate brachytherapy during the study period and 58 patients underwent chest radiography. Seed migration ...Continue Reading

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Citations

Feb 18, 2004·International Journal of Radiation Oncology, Biology, Physics·Henry F BlairQin-Sheng Chen
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