Importance of diagnostics in epidemic and pandemic preparedness

BMJ Global Health
Cassandra D Kelly-CirinoCatharina C Boehme

Abstract

Diagnostics are fundamental for successful outbreak containment. In this supplement, 'Diagnostic preparedness for WHO Blueprint pathogens', we describe specific diagnostic challenges presented by selected priority pathogens most likely to cause future epidemics. Some challenges to diagnostic preparedness are common to all outbreak situations, as highlighted by recent outbreaks of Ebola, Zika and yellow fever. In this article, we review these overarching challenges and explore potential solutions. Challenges include fragmented and unreliable funding pathways, limited access to specimens and reagents, inadequate diagnostic testing capacity at both national and community levels of healthcare and lack of incentives for companies to develop and manufacture diagnostics for priority pathogens during non-outbreak periods. Addressing these challenges in an efficient and effective way will require multiple stakeholders-public and private-coordinated in implementing a holistic approach to diagnostics preparedness. All require strengthening of healthcare system diagnostic capacity (including surveillance and education of healthcare workers), establishment of sustainable financing and market strategies and integration of diagnostics with ex...Continue Reading

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Citations

Jul 10, 2020·The Journal of Laryngology and Otology·Z MughalC E J Hall
Sep 17, 2020·International Journal of Environmental Research and Public Health·Elena Marbán-CastroAzucena Bardají
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Dec 24, 2021·Nature Biotechnology·Stefano OngarelloFay Betsou

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Methods Mentioned

BETA
ELISA
PCR

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