PMID: 9179763Jun 1, 1997Paper

Importance of sexual transmission of hepatitis C virus in seropositive pregnant women: a case-control study

Journal of Medical Virology
L SallerasN Galí

Abstract

The mode of hepatitis C virus (HCV) transmission in patients who deny parenteral exposure is still not understood. Seroprevalence studies of anti-HCV in sexually promiscuous populations and in spouses of infected patients have given contradictory results. We investigated the role of sexual transmission of HCV in a case-control study of risk factors for infection in a series of 43 anti-HCV positive pregnant women and 172 matched controls (4 for each case). In the univariate analysis, the following factors were associated significantly with anti-HCV seropositivity: low social class, unmarried, history of abortion, wounds which were sutured, tattooes, sharing toiletries with the partner, sexual contact outside the partnership without condom use, blood transfusion, and intravenous drug abuse, but only the last 3 factors remained significantly associated with HCV infection in multiple logistic regression analysis. The relative risk of HCV infection increased according to the increased number of sexual partners. Thus sexual transmission must be considered a possible mode of infection in HCV infected persons without parenteral exposures.

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Citations

Oct 2, 2013·Nature Reviews. Gastroenterology & Hepatology·Mark Thursz, Arnaud Fontanet
Apr 28, 2004·Infectious Diseases in Obstetrics and Gynecology·Youyin ChoyPeter G McGovern
Aug 10, 2001·Australian and New Zealand Journal of Public Health·C C TrasancosH Kelly
Nov 28, 2013·Infectious Disease Clinics of North America·Linda Gorgos
Dec 18, 2001·Journal of Medical Virology·A DomínguezL Salleras
Nov 1, 2006·Revue D'épidémiologie Et De Santé Publique·E Delarocque-AstagneauJ C Desenclos
Dec 14, 2006·Clinics in Liver Disease·Stephanie R Bialek, Norah A Terrault
Jun 25, 2009·Journal of Medical Virology·Tatjana Vilibic CavlekAdriana Vince
Jul 17, 2010·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Rania A Tohme, Scott D Holmberg
Sep 1, 2000·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·M P LimaM D Rocha
Aug 18, 2009·Revista Da Sociedade Brasileira De Medicina Tropical·Norma de Paula CavalheiroAntonio Alci Barone
Nov 21, 2007·Revista Do Instituto De Medicina Tropical De São Paulo·Norma de Paula Cavalheiro
May 7, 2004·The American Journal of Gastroenterology·Carmen VandelliAlessandro Zanetti
Sep 4, 2015·World Journal of Gastroenterology : WJG·Tatjana Vilibic-CavlekJasmina Vranes
Jul 14, 2001·Revista Do Instituto De Medicina Tropical De São Paulo·F M TenganA A Barone

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