Importing measured field fluences into the treatment planning system to validate a breathing synchronized DMLC-IMRT irradiation technique

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
D VerellenG Storme

Abstract

Recalculating dose distributions using measured IMRT fluence fields imported into the treatment planning system (TPS) to evaluate the technical feasibility of a prototype developed for breathing synchronized irradiation. DMLC-IMRT fluence patterns acquired on radiographic film, generated by the linac in non-gated and gated mode, have been imported into the TPS. The effect of dose blurring and possible interplay between organ motion and leaf motion, and the efficacy of a breathing synchronized irradiation technique (an adapted version of a commercially available image-guidance system: NOVALIS BODY/ExacTrac4.0, BrainLAB AG) have been evaluated using radiographic film mounted to a simple phantom simulating a breathing pattern of 16 cycles per minute and covering a distance of 4 cm to obtain the resulting fluence maps. Two situations have been investigated to illustrate this principle: (a) a tumor located close to the diaphragm to assess the influence of organ motion on the dose to the target volume as well as to the gastro-intestinal tract that presents a high risk at intersecting with the beam during the breathing cycle. (b) A mediastinal lesion requiring complicated fluence patterns. Importing measured fluence maps yielded highl...Continue Reading

References

Jul 1, 1999·International Journal of Radiation Oncology, Biology, Physics·J W WongA A Martinez
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Oct 31, 2000·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J WulfM Flentje
Jun 18, 2002·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Dirk VerellenGuy Storme
Aug 8, 2002·Physics in Medicine and Biology·Thomas BortfeldSteve B Jiang
Sep 5, 2002·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Nadine LinthoutGuy Storme
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Jan 11, 2005·Journal of Vascular and Interventional Radiology : JVIR·Johan de MeyAxel Bossuyt

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Citations

Aug 3, 2010·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·D VerellenM De Ridder
Apr 17, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Nadine LinthoutGuy Storme
Dec 18, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Dirk VerellenGuy Storme
Jul 21, 2006·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·D VerellenG Storme
Feb 15, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Tom DepuydtMark De Ridder
Nov 24, 2007·Nature Reviews. Cancer·Dirk VerellenGuy Storme
Jul 20, 2011·Acta Oncologica·Silje Mohn, Ellen Wasbø

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