Abstract
To investigate the effect of impregnation of poly(ethyl methacrylate) and tetrahydro-furfuryl methacrylate (PEM/THFM) polymeric delivery system with chlorhexidine or fluconazole on its shear bond strength (SBS) and water sorption. For SBS testing, 16 PEM/THFM discs impregnated with chlorhexidine (CHX), pure fluconazole (FLUp) or fluconazole from capsules (FLUc) and 16 drug-free control discs were prepared and bonded to heat-cured acrylic blocks. All discs were allowed to set for 24h at room temperature. After setting, half the discs (n=8) were tested immediately (Group 1). The other half was further incubated in water for 28 days at 37 °C before testing (Group 2). To evaluate water uptake, five PEM/THFM discs impregnated with CHX, FLUp or FLUc and five drug-free control discs were prepared and incubated in water. Mass changes were measured up to six months. The mean SBS for control, FLUp, CHX and FLUc discs were 4.01, 3.85, 3.29 and 2.26 MPa, respectively for Group 1. Group 2 showed significantly lower SBS (P≤0.05). All failures were adhesive. The percentage mass change due to water sorption ranged significantly from 12% for control to 27% for FLUc (P≤0.05). A strong negative correlation between the extent of water absorption a...Continue Reading
References
Apr 1, 1978·Journal of Oral Rehabilitation·R G Jagger
Nov 1, 1976·Journal of Biomedical Materials Research·E P LautenschlagerC L Nelson
Sep 1, 1991·Biomaterials·M P Patel, M Braden
Sep 1, 1991·Biomaterials·M P Patel, M Braden
May 1, 1986·International Endodontic Journal·G J PearsonC Longman
Jul 1, 1985·Biomaterials·I M Brook, R van Noort
Mar 1, 1981·Journal of Oral Rehabilitation·M Addy
Mar 1, 1981·Journal of Oral Rehabilitation·M Addy, R Handley
Oct 1, 1995·Journal of Dentistry·A DoğanA Usanmaz
Apr 16, 1999·Biomaterials·P D RiggsM P Patel
Feb 3, 2000·Biomaterials·R M Wyre, S Downes
Feb 3, 2000·Biomaterials·P D RiggsM Patel
Mar 15, 2001·Biomaterials·G A HutcheonS Downes
Dec 11, 2002·The Journal of Prosthetic Dentistry·José Renato Ribeiro PintoMauro Antôonio de Arruda Nóbilo
Sep 1, 1961·The Journal of the American Dental Association·R G CRAIG, P GIBBONS
Feb 12, 2008·The Journal of Prosthetic Dentistry·Ayse Mese, Kahraman G Guzel
Feb 4, 2010·Dental Materials : Official Publication of the Academy of Dental Materials·Muhanad M Hatamleh, David C Watts
Jun 15, 2011·Journal of Prosthodontic Research·Takeshi MaedaYasumasa Akagawa
Mar 7, 2012·Journal of Dentistry·Nesreen SalimRiina Rautemaa
Citations
Nov 23, 2012·The Journal of Antimicrobial Chemotherapy·N SalimR Rautemaa
Dec 5, 2012·Dental Materials Journal·Nesreen SalimNick Silikas
Nov 26, 2013·Journal of Dentistry·Alaa Al-HaddadJulian D Satterthwaite
Dec 17, 2014·Journal of Dentistry·Sarah J GarnerMichele E Barbour