PMID: 15354979Sep 10, 2004Paper

Improved anemia and reduced erythropoietin need by medical or surgical intervention of secondary hyperparathyroidism in hemodialysis patients

Renal Failure
Chun-Liang LinChiu-Ching Huang

Abstract

The available literature is still controversial and shows that surgical (parathyroidectomy, PTX) or medical (calcitriol) treatment actually improved or even corrected the rhEPO-resistant anemia of ESRD patients with severe SHP. The aims of this study were to 1) assess the influence of SHP on hematological parameters in ESRD patients, 2) evaluate whether or not calcitriol could improve anemia and reduce the need of erythropoietin in dialysis patients, and 3) investigate the longitudinal effect of a parathyroidectomy for 6 months on regarding any improvements in calcitriol-refractory ESRD patients. 37 chronic hemodialysis patients in Chang Gung Memorial Hospital Dialysis Unit were divided into two groups: patients with SHP (iPTH>300 pg/mL) and patients without SHP (ipTH<300 pg/mL) before calcitriol therapy was applied. Sixteen patients remain with a status of hyperparathyroidism and were considered candidates for calcitriol therapy. Furthermore, we divided the patients according to the response of HPT to calcitriol into responding patients and nonresponding patients. Among nonresponder groups, three patients agreed to accept surgical intervention to treat their hyperparathyroidism status. The phosphate levels and serum alkaline p...Continue Reading

References

Nov 1, 1995·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·F LlachS Cerezo
Jan 1, 1995·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·T B Drüeke
Jan 1, 1995·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·B Danielson
Jan 1, 1996·Nephron·S NomuraH Nagahana
Oct 30, 1998·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·S MandolfoE Imbasciati
Aug 18, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·G Sunder-Plassmann, W H Hörl
Mar 29, 2002·American Journal of Surgery·Chikao YasunagaTadanobu Goya
Jul 2, 2002·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Tilman B Drüeke, Kai-Uwe Eckardt

❮ Previous
Next ❯

Citations

Oct 10, 2009·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Cheryl P Sanchez
Sep 29, 2015·Current Opinion in Endocrinology, Diabetes, and Obesity·Ellen M Smith, Vin Tangpricha
Mar 8, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Andrea IcardiMario Cozzolino
Mar 26, 2013·BMC Nephrology·Andreas SchneiderChristiane Drechsler
Mar 2, 2011·Transplantation·Csaba P KovesdyMiklos Z Molnar
Apr 17, 2015·The British Journal of Nutrition·Ellen M SmithVin Tangpricha
May 19, 2020·EMBO Reports·Hans-Willem Snoeck
Feb 5, 2010·Kidney International·Neha M PatelMyles Wolf

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.