Improved assessment of arterial stiffness using corrected cardio-ankle vascular index (CAVI0 ) in overweight adolescents with white-coat and essential hypertension

Scandinavian Journal of Clinical and Laboratory Investigation
Michal MestanikIngrid Tonhajzerova

Abstract

Arterial stiffness is a marker of vascular damage. Although adiposity increases cardiovascular risk, the relationship between paediatric overweight and arterial stiffness is unclear. The study aimed to evaluate the simultaneous effect of hypertension and overweight on arterial stiffness using cardio-ankle vascular index (CAVI) and related novel, theoretically blood pressure (BP)-independent, index CAVI0. CAVI and CAVI0 were measured in 140 adolescent boys (16.0 ± 1.9 years) divided into age-matched groups: normal-weight normotensives, overweight normotensives, overweight white-coat hypertensives, and overweight essential hypertensives. Overweight normotensives had significantly lower CAVI and CAVI0 compared to normal-weight normotensives (4.81 ± 0.64 vs. 5.33 ± 0.66, p < .01; 7.10 ± 0.99 vs. 7.81 ± 1.00, p < .01, respectively). CAVI and CAVI0 in overweight essential hypertensives showed no significant difference compared to normal-weight normotensives and were significantly higher compared to overweight normotensives (5.32 ± 0.77 vs. 4.81 ± 0.64, p < .01; 7.77 ± 1.19 vs. 7.10 ± 0.99, p < .01, respectively). CAVI, but not CAVI0, was associated positively with diastolic pressure (0.022 mmHg-1, p = .002) and negatively with pulse ...Continue Reading

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Citations

Apr 16, 2019·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Jinju KimYoung Min Choi
May 10, 2019·Journal of Atherosclerosis and Thrombosis·Kohji ShiraiKoji Takahashi
Jun 5, 2019·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Ingrid TonhajzerovaMichal Mestanik
Apr 2, 2019·Journal of Atherosclerosis and Thrombosis·Barbora CzippelovaMichal Javorka
Aug 12, 2020·Clinical and Experimental Pediatrics·Ronald J Headid Iii, Song-Young Park

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