Improved Function With Enhanced Protein Intake per Meal: A Pilot Study of Weight Reduction in Frail, Obese Older Adults

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Kathryn N Porter StarrConnie W Bales

Abstract

Obesity is a significant cause of functional limitations in older adults; yet, concerns that weight reduction could diminish muscle along with fat mass have impeded progress toward an intervention. Meal-based enhancement of protein intake could protect function and/or lean mass but has not been studied during geriatric obesity reduction. In this 6-month randomized controlled trial, 67 obese (body mass index ≥30kg/m(2)) older (≥60 years) adults with a Short Physical Performance Battery score of 4-10 were randomly assigned to a traditional (Control) weight loss regimen or one with higher protein intake (>30g) at each meal (Protein). All participants were prescribed a hypo-caloric diet, and weighed and provided dietary guidance weekly. Physical function (Short Physical Performance Battery) and lean mass (BOD POD), along with secondary measures, were assessed at 0, 3, and 6 months. At the 6-month endpoint, there was significant (p < .001) weight loss in both the Control (-7.5±6.2kg) and Protein (-8.7±7.4kg) groups. Both groups also improved function but the increase in the Protein (+2.4±1.7 units; p < .001) was greater than in the Control (+0.9±1.7 units; p < .01) group (p = .02). Obese, functionally limited older adults undergoing...Continue Reading

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Citations

May 7, 2016·Nutrients·Kathryn N Porter StarrConnie W Bales
Sep 14, 2016·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Stephen B Kritchevsky
Jun 21, 2018·Journal of Nutrition in Gerontology and Geriatrics·Kathryn N Porter StarrConnie W Bales
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Jan 16, 2019·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Cilla Haywood, Priya Sumithran
Feb 27, 2019·Journal of Nutrition in Gerontology and Geriatrics·Rima Itani Al-Nimr
Feb 28, 2019·Journal of Nutrition in Gerontology and Geriatrics·Kathryn N Porter StarrConnie W Bales
Mar 9, 2019·Journal of Nutrition in Gerontology and Geriatrics·Denise K HoustonBarbara J Nicklas
Nov 16, 2019·Nature Reviews. Endocrinology·Bettina MittendorferLuigi Fontana
Oct 18, 2016·Current Opinion in Clinical Nutrition and Metabolic Care·Ilse ReindersLaura Schaap
Jul 17, 2020·The Proceedings of the Nutrition Society·G M LynchH M Roche
Apr 17, 2018·Advances in Nutrition·Connie W Bales, Kathryn N Porter Starr
Jan 11, 2019·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Kristen M BeaversDaniel P Beavers
Sep 4, 2020·Advances in Nutrition·Adela Hruby, Paul F Jacques
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