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Improved genome inference in the MHC using a population reference graph

bioRxiv

Jul 8, 2014

Alexander DiltheyGil McVean

Abstract

In humans and many other species, while much is known about the extent and structure of genetic variation, such information is typically not used in assembling novel genomes. Rather, a single reference is used against which to map reads, which can lead to poor characterisation of region...read more

Mentioned in this Paper

Genome
Recombination, Genetic
Chromosomes, Human, Pair 6
Major Histocompatibility Complex
Chromosomes
Structure
Simulation
Major histocompatibility complex protein
Species
Analysis
35
2
Paper Details
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Improved genome inference in the MHC using a population reference graph

bioRxiv

Jul 8, 2014

Alexander DiltheyGil McVean

PMID: 990006973

DOI: 10.1101/006973

Abstract

In humans and many other species, while much is known about the extent and structure of genetic variation, such information is typically not used in assembling novel genomes. Rather, a single reference is used against which to map reads, which can lead to poor characterisation of region...read more

Mentioned in this Paper

Genome
Recombination, Genetic
Chromosomes, Human, Pair 6
Major Histocompatibility Complex
Chromosomes
Structure
Simulation
Major histocompatibility complex protein
Species
Analysis
35
2
Paper Details
References
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  • Citations
  • finger pointing at paper

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    We're still populating references for this paper, please check back later.
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