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Improved genome inference in the MHC using a population reference graph

bioRxiv

Jul 8, 2014

Alexander T. DiltheyG A.T. McVean

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Abstract

In humans and many other species, while much is known about the extent and structure of genetic variation, such information is typically not used in assembling novel genomes. Rather, a single reference is used against which to map reads, which can lead to poor characterisation of region...read more

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  • Improved genome inference in the MHC using a population reference graph

    bioRxiv

    Jul 8, 2014

    Alexander T. DiltheyG A.T. McVean

    PMID: 990006973

    DOI: 10.1101/006973

    Abstract

    In humans and many other species, while much is known about the extent and structure of genetic variation, such information is typically not used in assembling novel genomes. Rather, a single reference is used against which to map reads, which can lead to poor characterisation of region...read more

    35
    2
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