Improved growth performance, food efficiency, and lysine availability in growing rats fed with lysine-biofortified rice

Scientific Reports
Qing-Qing YangSamuel Sai-Ming Sun


Rice is an excellent source of protein, and has an adequate balance of amino acids with the exception of the essential amino acid lysine. By using a combined enhancement of lysine synthesis and suppression of its catabolism, we had produced two transgenic rice lines HFL1 and HFL2 (High Free Lysine) containing high concentration of free lysine. In this study, a 70-day rat feeding study was conducted to assess the nutritional value of two transgenic lines as compared with either their wild type (WT) or the WT rice supplemented with different concentrations of L-lysine. The results revealed that animal performance, including body weight, food intake, and food efficiency, was greater in the HFL groups than in the WT group. Moreover, the HFL diets had increased protein apparent digestibility, protein efficiency ratio, and lysine availability than the WT diet. Based on the linear relationship between dietary L-lysine concentrations and animal performance, it indicated that the biological indexes of the HFL groups were similar or better than that of the WT20 group, which was supplemented with L-lysine concentrations similar to those present in the HFL diets. Therefore, lysine-biofortified rice contributed to improved growth performanc...Continue Reading


Jan 1, 1991·Life Sciences·J E Morley, J F Flood
May 1, 1990·The British Journal of Nutrition·D N SalterR J Elliott
Aug 5, 1997·Proceedings of the National Academy of Sciences of the United States of America·L MolvigT J Higgins
Jan 10, 1998·British Journal of Pharmacology·L LiaudetF Feihl
Aug 18, 2000·Journal of Animal Science·P R O'QuinnT T Lohrmann
Jul 31, 2004·The Journal of Nutrition·Andrea J FascettiQuinton R Rogers
Dec 21, 2006·Plant Biotechnology Journal·John M BakerMichael H Beale
Apr 4, 2007·The British Journal of Nutrition·Peng LiGuoyao Wu
May 13, 2008·The American Journal of Clinical Nutrition·D Joe MillwardGertjan Schaafsma
Jul 19, 2008·Journal of Agricultural and Food Chemistry·Jin ZhuPatrick J Tranel
Nov 13, 2008·Cytotechnology·D DattaV Chandran
May 2, 2009·Molecular Endocrinology·Susan C Wu, Yi Zhang
Apr 8, 2010·Amino Acids·R A Azevedo, P Arruda
May 6, 2011·Plant Physiology·Hiroaki SaikaSeiichi Toki
Oct 11, 2012·Journal of Animal Science·S K GatrellK P Blemings
Nov 14, 2012·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Karen P ScottSylvia H Duncan
Jan 3, 2013·Plant Biotechnology Journal·Xiaohang LongSamuel S M Sun
Feb 13, 2013·Journal of the Science of Food and Agriculture·Maozhi TangKunlun Huang
Apr 3, 2013·Mini Reviews in Medicinal Chemistry·S M HosseiniM R Mozafari
Apr 17, 2013·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Minh Van NguyenIvar Rønnestad
Jan 15, 2014·Nature Neuroscience·Daniel BorotaMichael A Yassa
Dec 17, 2014·Plant Foods for Human Nutrition·Elba Graciela AguilarNora Lilian Escudero
Dec 17, 2014·Plant Molecular Biology·H W WongS S M Sun
Jan 13, 2015·Molecular Plant·Miyako KusanoKazuki Saito
Feb 29, 2016·Tropical Animal Health and Production·K Naga Raja KumariS Venkata Rama Rao
Mar 13, 2016·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Jesse BertinatoChao-Wu Xiao
Jul 13, 2016·Journal of Experimental Botany·Wenyi Wang, Gad Galili

❮ Previous
Next ❯


Jan 10, 2020·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Mingchao ZhaoHao Chen
May 22, 2019·Public Health Nutrition·Christopher D GoldenSamuel S Myers
Dec 9, 2020·Critical Reviews in Food Science and Nutrition·Renuka Aggarwal, Kiran Bains
Feb 26, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Prakash Raj PandeyaHyun-Ju Jung

❮ Previous
Next ❯

Methods Mentioned


Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Epigenetics Insights from Twin Studies

Find the latest research on epigenetics and twin studies here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Related Papers

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
Qing-Qing YangQiao-Quan Liu
© 2021 Meta ULC. All rights reserved