PMID: 2570Feb 26, 1976

Improved histological localization of GABA-transaminase activity in rat cerebellar cortex after aldehyde fixation

Histochemistry
J C Hyde, N Robinson

Abstract

A method for the chemical fixation of the enzyme GABA-transaminase in nervous tissue is described. It is shown that after perfusion with a formaldehyde/glutaraldehyde fixative, activity of the enzyme in cerebellar cortex is demonstrable whilst cellular morphology is preserved. Results from the improved technique have shown new sites of GABA-transaminase activity in cerebellar cortex. In view of these results a special function for glial cells in this area of brain has been suggested.

References

Jul 1, 1971·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·K L SimsF E Bloom
Nov 1, 1974·Journal of Neurocytology·V Chan-PalayS M Billings-Gagliardi
Aug 1, 1974·Journal of Neurochemistry·J C Hyde, N Robinson
Apr 1, 1968·Journal of Neurochemistry·A WaksmanE Roberts
Feb 16, 1972·Nature: New Biology·M J Neal, L L Iversen
Apr 1, 1972·The Journal of Cell Biology·C Peracchia, B S Mittler
Mar 29, 1974·Nature·J C Hyde, N Robinson
Aug 1, 1971·Experimental Cell Research·G E Wise, C J Flickinger
Apr 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·K KuriyamaE Roberts
Sep 1, 1971·Journal of Molecular and Cellular Cardiology·S H LeeG Rona
Apr 1, 1968·The Journal of Cell Biology·R S Cotran, M J Karnovsky
Oct 1, 1966·Journal of Neurochemistry·R BalázsJ R Harwood

Citations

May 1, 1993·The Histochemical Journal·P Kugler
Jan 1, 1981·Histochemistry·S Y Al-Ali, N Robinson
Nov 11, 1982·Brain Research·S R VincentE G McGeer
Mar 1, 1980·Neuroscience Letters·S R VincentE G McGeer

Related Concepts

4-Aminobutyrate aminotransferase
Transaminases
Metazoa
Cerebellar Cortex Structure
Formalin
Gammalon
Sonacide
Cytochemistry
Histological Techniques
Hydrogen-Ion Concentration

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