Improved insulin sensitivity and lower postprandial triglyceride concentrations after cold-pressed turnip rapeseed oil compared to cream in patients with metabolic syndrome

Diabetology & Metabolic Syndrome
Harri Juhani SaarinenAri Palomäki

Abstract

The aim of this study was to compare acute effects of turnip rapeseed oil rich with mono- and polyunsaturated fatty acids and cream on postprandial triglyceride levels and post-glucose load measures of insulin sensitivity in population of men with metabolic syndrome. This open-label balanced crossover study included 37 men with metabolic syndrome. They underwent an oral glucose-fat tolerance test where they ingested 75 g of glucose with either 240 mL of cream or 84 mL of turnip rapeseed oil depending on the study arm. Hourly postprandial blood samples were drawn up to 5 h after this oral glucose-fat tolerance test to determine the changes in triglyceride concentrations and to measure insulin sensitivity. Changes in insulin sensitivity were calculated with different insulin sensitivity indices (OGIS, Stumvoll, Gutt and McAuley scores) derived from measured insulin and glucose concentrations. The oral glucose-fat tolerance test was preceded by a period during which the participants consumed a daily portion of either 35 mL of turnip rapeseed oil or 37.5 g of butter depending on the study arm in addition to their habitual diets. Both dietary periods lasted from 6 to 8 weeks. After an 8-week wash-out period the subjects crossed over...Continue Reading

References

Mar 1, 1992·Diabetes Care·R A DeFronzoE Ferrannini
Mar 31, 2000·Diabetes Research and Clinical Practice·M GuttJ B Marks
Jul 6, 2000·Circulation·UNKNOWN Bezafibrate Infarction Prevention (BIP) study
Apr 6, 2001·Diabetes Care·K A McAuleyA W Duncan
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Dec 4, 2002·JAMA : the Journal of the American Medical Association·Hanna-Maaria LakkaJukka T Salonen
May 14, 2003·Archives of Internal Medicine·Lynn E EberlyUNKNOWN Multiple Risk Factor Intervention Trial Research Group
Jul 20, 2007·JAMA : the Journal of the American Medical Association·Sandeep BansalPaul M Ridker
Oct 30, 2009·The Journal of Nutrition·Viswanathan SaraswathiAlyssa H Hasty
Apr 28, 2010·Clinical Science·Pablo Perez-MartinezJose Lopez-Miranda
Jul 27, 2010·Journal of the American Dietetic Association·Marina Campos AraujoRosangela Alves Pereira
May 4, 2011·World Journal of Diabetes·Bhawna Singh, Alpana Saxena
Jul 9, 2011·Cardiovascular Diabetology·Sameer AnsarPeter D Reaven
Nov 5, 2011·Journal of the American College of Cardiology·Dariush Mozaffarian, Jason H Y Wu
May 25, 2013·The Journal of Clinical Endocrinology and Metabolism·Jason H Y WuDariush Mozaffarian
Jul 12, 2014·The New England Journal of Medicine·Martin J LandrayJane Armitage
Aug 28, 2016·European Heart Journal·Alberico L CatapanoUNKNOWN ESC Scientific Document Group
Jun 8, 2017·Annals of Medicine·Tiina Vilmi-KeräläAri Palomäki
Aug 13, 2017·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Harri Juhani SaarinenAri Palomäki

❮ Previous
Next ❯

Software Mentioned

Excel
CPTRO

Related Concepts

Related Feeds

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Biomarkers for Cardiovascular Risk Assessment

Sensitive and accurate biomarkers used in cardiovascular risk prediction can potentially be used to manage the risk of cardiovascular disease. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here.