Improved measurement of pressure gradients in aortic coarctation by magnetic resonance imaging

Journal of the American College of Cardiology
J N OshinskiR I Pettigrew

Abstract

This study evaluated whether magnetic resonance imaging (MRI) and magnetic resonance (MR) phase velocity mapping could provide accurate estimates of stenosis severity and pressure gradients in aortic coarctation. Clinical management of aortic coarctation requires determination of lesion location and severity and quantification of the pressure gradient across the constricted area. Using a series of anatomically accurate models of aortic coarctation, the laboratory portion of this study found that the loss coefficient (K), commonly taken to be 4.0 in the simplified Bernoulli equation delta P = KV2, was a function of stenosis severity. The values of the loss coefficient ranged from 2.8 for a 50% stenosis to 4.9 for a 90% stenosis. Magnetic resonance imaging and MR phase velocity mapping were then used to determine coarctation severity and pressure gradient in 32 patients. Application of the new severity-dependent loss coefficients found that pressure gradients deviated from 1 to 17 mm Hg compared with calculations made with the commonly used value of 4.0. Comparison of MR estimates of pressure gradient with Doppler ultrasound estimates (in 22 of 32 patients) and with catheter pressure measurements (in 6 of 32 patients) supports th...Continue Reading

References

Nov 1, 1992·Journal of Magnetic Resonance Imaging : JMRI·J N OshinskiR I Pettigrew
Jan 1, 1992·Magnetic Resonance Imaging·R G de Graaf, J P Groen
Jul 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·M H Buonocore, H Bogren
Jan 1, 1990·Journal of Biomechanics·E G CapeR A Levine
May 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·D N FirminD B Longmore
Feb 1, 1989·American Heart Journal·A L PucilloM V Herman
Mar 1, 1989·Journal of the American College of Cardiology·R A LevineA E Weyman
Feb 1, 1987·AJR. American Journal of Roentgenology·R I PettigrewM E Bernardino
May 1, 1987·Ultrasound in Medicine & Biology·H Rijsterborgh, J Roelandt
Sep 1, 1987·Journal of Vascular Surgery·D N KuC K Zarins
Jun 1, 1986·Journal of the American College of Cardiology·G R Marx, H D Allen
Mar 1, 1986·International Journal of Cardiology·Y ZhangS Nitter-Hauge
May 1, 1986·Journal of the American College of Cardiology·R A BoxerH L Stein
Jul 1, 1973·Journal of Biomechanics·D F Young, F Y Tsai
Sep 1, 1970·British Heart Journal·M Campbell
Jan 1, 1984·Journal of the American College of Cardiology·M BergerE Goldberg
Jan 1, 1984·Journal of the American College of Cardiology·J G Stevenson, I Kawabori
May 1, 1984·Journal of the American College of Cardiology·D KosturakisL M Valdes-Cruz
Jun 1, 1984·Journal of Computer Assisted Tomography·P van Dijk
Feb 1, 1996·Journal of the American College of Cardiology·P S RaoA D Wilson

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Citations

Nov 5, 1999·Journal of Magnetic Resonance Imaging : JMRI·A A RoestA de Roos
Jul 9, 2005·European Radiology·Peter D GatehouseDavid N Firmin
Apr 2, 2010·Journal of Digital Imaging·Per Thunberg, Anders Kähäri
Apr 13, 1999·Radiologic Clinics of North America·S B Greenberg, S K Sandhu
Jul 31, 1998·Seminars in Roentgenology·A M HubbardM A Fogel
Jul 31, 1998·Seminars in Roentgenology·G G Hartnell, M Notarianni
Jul 31, 1998·Seminars in Roentgenology·G R Marx, T Geva
Jun 15, 2013·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Sohrab FratzAndrew J Powell
Feb 24, 2009·AJR. American Journal of Roentgenology·Monvadi B SrichaiVivian S Lee
Dec 27, 2011·The American Journal of Cardiology·Stefano MuzzarelliJeffery Joshua Meadows
Feb 24, 2009·Seminars in Roentgenology·Evrim Bengi Turkbey, David A Dombroski
Mar 26, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jelena BockMichael Markl
Feb 21, 2006·The Annals of Thoracic Surgery·Tiffany J RiehleW James Parks
Aug 10, 2015·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Krishna S NayakSubha V Raman
Nov 2, 2002·Journal of Magnetic Resonance Imaging : JMRI·Per ThunbergMatts Karlsson
Feb 11, 2016·World Journal of Clinical Pediatrics·Frances M MitchellClaire E Raphael
Feb 9, 2005·Circulation·James C NielsenTal Geva
Feb 5, 2019·Journal of Magnetic Resonance Imaging : JMRI·Kevin BouaouNadjia Kachenoura
Aug 12, 2009·Congenital Heart Disease·François MarcottePaul Khairy
Nov 5, 1999·Journal of Magnetic Resonance Imaging : JMRI·R I PettigrewW T Dixon
Aug 16, 2017·Medical & Biological Engineering & Computing·Francisco J Londono-HoyosPatrick Segers
May 27, 2020·Medical & Biological Engineering & Computing·Benedikt FrankeL Goubergrits
Aug 22, 2014·Current Treatment Options in Cardiovascular Medicine·Mohammed Haris Umer UsmanChristian Witzke-Sanz
Oct 3, 2006·Clinical Cardiology·Warren J Manning
Nov 10, 2020·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Tim LeinerDudley J Pennell
Jun 27, 2014·The International Journal of Artificial Organs·Giovanni BiglinoUNKNOWN Mocha Collaborative Group
Dec 27, 2005·International Journal of Cardiology·Joachim G EichhornHerbert E Ulmer
Oct 24, 2007·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·A Cabrera DuroJ I Aramendi Gallardo

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