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Improved methods for multi-trait fine mapping of pleiotropic risk loci

Bioinformatics

Nov 1, 2016

Gleb KichaevBogdan Pasaniuc

Abstract

Genome-wide association studies (GWAS) have identified thousands of regions in the genome that contain genetic variants that increase risk for complex traits and diseases. However, the variants uncovered in GWAS are typically not biologically causal, but rather, correlated to the true c...read more

Mentioned in this Paper

Computer Software
Genome-Wide Association Study
Research
Follow-up
Genome
Dysequilibrium Syndrome
Bio-Informatics
Genome Mapping
Computer Programs and Programming
Genomics
6
74
Paper Details
References
  • References30
  • Citations17
123
  • References30
  • Citations17
12

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Improved methods for multi-trait fine mapping of pleiotropic risk loci

Bioinformatics

Nov 1, 2016

Gleb KichaevBogdan Pasaniuc

PMID: 27663501

DOI: 10.1093/bioinformatics/btw615

Abstract

Genome-wide association studies (GWAS) have identified thousands of regions in the genome that contain genetic variants that increase risk for complex traits and diseases. However, the variants uncovered in GWAS are typically not biologically causal, but rather, correlated to the true c...read more

Mentioned in this Paper

Computer Software
Genome-Wide Association Study
Research
Follow-up
Genome
Dysequilibrium Syndrome
Bio-Informatics
Genome Mapping
Computer Programs and Programming
Genomics
6
74

Similar Papers Found In These Feeds

Lipidomics

Lipidomics is a branch of metabolomics that comprehensively analyses lipids in biological systems to determine the molecules with which they interact and their function within the cell. Here is the latest research.

Related Papers

Bioinformatics

SCAN: SNP and copy number annotation

BioinformaticsNovember 26, 2009
Eric R GamazonNancy J Cox
Paper Details
References
  • References30
  • Citations17
123
  • References30
  • Citations17
12
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