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Improved methods for multi-trait fine mapping of pleiotropic risk loci

bioRxiv

May 21, 2016

Gleb KichaevBogdan Pasaniuc

Abstract

Genome-wide association studies (GWAS) have identified thousands of regions in the genome that contain genetic variants that increase risk for complex traits and diseases. However, the variants uncovered in GWAS are typically not biologically causal, but rather, correlated to the true c...read more

Mentioned in this Paper

Genome-Wide Association Study
Follow-up
Genome
Dysequilibrium Syndrome
Mapping, Vessel
Simulation
Lipids
Locus
EAF2
Single Nucleotide Polymorphism
13
13
Paper Details
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Improved methods for multi-trait fine mapping of pleiotropic risk loci

bioRxiv

May 21, 2016

Gleb KichaevBogdan Pasaniuc

PMID: 990054684

DOI: 10.1101/054684

Abstract

Genome-wide association studies (GWAS) have identified thousands of regions in the genome that contain genetic variants that increase risk for complex traits and diseases. However, the variants uncovered in GWAS are typically not biologically causal, but rather, correlated to the true c...read more

Mentioned in this Paper

Genome-Wide Association Study
Follow-up
Genome
Dysequilibrium Syndrome
Mapping, Vessel
Simulation
Lipids
Locus
EAF2
Single Nucleotide Polymorphism
13
13
Paper Details
References
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  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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