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Improved methods for multi-trait fine mapping of pleiotropic risk loci

bioRxiv

May 21, 2016

Gleb KichaevBogdan Pasaniuc

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Abstract

Genome-wide association studies (GWAS) have identified thousands of regions in the genome that contain genetic variants that increase risk for complex traits and diseases. However, the variants uncovered in GWAS are typically not biologically causal, but rather, correlated to the true c...read more

Mentioned in this Paper

Mapping, Vessel
BAT Loci
Lipids
Validation
Simulation
Single Nucleotide Polymorphism
Dysequilibrium Syndrome
Genetic Linkage
Organs at Risk
Genome
13
4
Paper Details
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  • Improved methods for multi-trait fine mapping of pleiotropic risk loci

    bioRxiv

    May 21, 2016

    Gleb KichaevBogdan Pasaniuc

    PMID: 990054684

    DOI: 10.1101/054684

    Abstract

    Genome-wide association studies (GWAS) have identified thousands of regions in the genome that contain genetic variants that increase risk for complex traits and diseases. However, the variants uncovered in GWAS are typically not biologically causal, but rather, correlated to the true c...read more

    Mentioned in this Paper

    Mapping, Vessel
    BAT Loci
    Lipids
    Validation
    Simulation
    13
    4
    Paper Details
    References
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      We're still populating references for this paper, please check back later.
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