PMID: 7539954Mar 1, 1995Paper

Improved microscopical diagnosis of pulmonary tuberculosis in developing countries

Transactions of the Royal Society of Tropical Medicine and Hygiene
N GebreH Miörner

Abstract

The diagnosis of pulmonary tuberculosis (TB) relies on the bacteriological examination of sputum. However, microscopy of smears made directly from sputum has a low sensitivity and there is an urgent need for improved methods. We have compared microscopy of smears made directly from sputum with microscopy after liquefaction of sputum with household bleach (NaOCl) and concentration of bacteria by centrifugation. In 3 studies performed in Ethiopia and India, the use of the NaOCl method increased the number of samples positive for acid-fast bacilli by more than 100%. The technique is appropriate for developing countries and its application would increase the efficiency of TB control programmes. As a potent disinfectant, NaOCl also has the advantage of lowering the risk of laboratory infection.

References

Nov 1, 1991·The American Review of Respiratory Disease·K D EisenachJ T Crawford
Mar 1, 1984·Reviews of Infectious Diseases·B A LipskyJ J Plorde
Mar 1, 1949·American Journal of Clinical Pathology·H J CORPER, C R NELSON

❮ Previous
Next ❯

Citations

May 9, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S I EyangohA Van Deun
Feb 24, 2001·Transactions of the Royal Society of Tropical Medicine and Hygiene·J BruchfeldL Lindquist
Jul 1, 1997·Transactions of the Royal Society of Tropical Medicine and Hygiene·A D HarriesP Nunn
Jul 1, 1997·Transactions of the Royal Society of Tropical Medicine and Hygiene·D Wilkinson, A W Sturm
Jul 1, 1997·Transactions of the Royal Society of Tropical Medicine and Hygiene·D WilkinsonA W Sturm
Dec 16, 1998·Transactions of the Royal Society of Tropical Medicine and Hygiene·C HabeenzuA F Fleming
Jan 1, 1997·Pharmacology & Therapeutics·A D Harries
Apr 11, 2001·Journal of Microbiological Methods·B HamasurS B Svenson
Jun 4, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·John WalleyAhmed Matovu
Apr 28, 2010·Journal of Clinical Microbiology·A CattamanchiK R Steingart
Feb 22, 2008·BMC Public Health·Mecky MateeC Fordham von Reyn
Jun 1, 1997·Medical Anthropology Quarterly·N L Vecchiato
Jan 1, 2008·Infection and Drug Resistance·Nora MorcilloJuan Carlos Palomino
Oct 5, 2010·The American Journal of Tropical Medicine and Hygiene·Leopold G LehmanCharles F Bilong Bilong
May 3, 2003·The Lancet Infectious Diseases·Kamran SiddiqiJohn Walley
Nov 13, 1998·Proceedings of the National Academy of Sciences of the United States of America·C J Murray, J A Salomon
Dec 23, 1995·Lancet·S B Squire
Mar 24, 2006·Tropical Medicine & International Health : TM & IH·Daniel EliasSven Britton
Nov 8, 2014·Laboratory Medicine·Johnson Makaen, Tobbias Maure
Jul 6, 2013·Memórias do Instituto Oswaldo Cruz·Cleoni Alves Mendes de LimaMaria Manuela da Fonseca Moura
May 17, 2018·Revista Da Sociedade Brasileira De Medicina Tropical·José Luiz de Oliveira MagalhãesAlzira Maria Paiva de Almeida
Sep 30, 2006·The Lancet Infectious Diseases·Karen R SteingartMadhukar Pai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.