Improved outcomes in paediatric anaesthesia: contributing factors.

Pediatric Surgery International
Mostafa SomriIbrahim Matter

Abstract

To discuss developments in paediatric anaesthesia and explore the factors which have contributed to improved anaesthetic-related patient outcomes. Narrative review of findings in the literature retrieved from MEDLINE/Pubmed and manual search. Adverse perioperative outcomes related to anaesthesia have been extensively debated over the past few decades, with studies implicating factors such as major human error and equipment failure. Case series and event registries have enlightened physicians on sources of error and patient risk factors such as extremes of age, comorbidity and emergent circumstances. Anaesthetic-related deaths in children fell from 6.4 per 10,000 anaesthetics in the early 1950s to as low as 0.1 per 10,000 anaesthetics by the end of the century. Advances in anaesthetic agents, techniques, monitoring technologies and training programmes in paediatric anaesthesia play a vital role in driving this downward trend. Despite substantial progress, there is still much room for improvement in areas such as adverse-event reporting, anaesthetic-related risk and late neurocognitive outcomes. Systematic reviews comparing paediatric patient outcomes after neuroaxial block versus general anaesthesia are currently unavailable. Th...Continue Reading

References

Dec 1, 1978·Anesthesiology·J B CooperB McPeek
Nov 1, 1991·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·T Nakamura, M Takasaki
Nov 1, 1991·Journal of Clinical Anesthesia·R L KeenanK Dawson
Feb 1, 1990·Anesthesia and Analgesia·M M CohenP G Duncan
Mar 17, 1989·JAMA : the Journal of the American Medical Association·F W CheneyR J Ward
Jan 1, 1988·International Anesthesiology Clinics·K J Anand, M P Ward-Platt
Apr 1, 1987·Anesthesiology·C D KurthJ J Downes
Aug 22, 1986·JAMA : the Journal of the American Medical Association·J H EichhornR G Seeman
Apr 26, 1985·JAMA : the Journal of the American Medical Association·R L Keenan, C P Boyan
Mar 1, 1984·Anesthesia and Analgesia·J C AbajianJ E Mazuzan
May 1, 1995·Acta Anaesthesiologica Scandinavica·G P JohannessonS G Lindahl
Mar 1, 1995·Journal of Clinical Monitoring·R C Morell
Oct 1, 1994·British Journal of Anaesthesia·P A StoddartR Bingham
May 1, 1994·Anesthesiology·R L KeenanP M Simpson
Mar 1, 1993·Anesthesiology·J P MorrayF W Cheney
Sep 1, 1996·Anaesthesia·A L RobinsonM A Stokes
May 1, 1997·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·R K WilliamsJ C Abajian
Jan 13, 2000·Paediatric Anaesthesia·J D Tobias
Mar 17, 2000·BMJ : British Medical Journal·P Barach, S D Small
Apr 27, 2000·Anesthesia and Analgesia·K L PetersonB A Reitz
Jun 30, 2000·BMJ : British Medical Journal·L Marsh, T M Dawson
Oct 26, 2000·Anesthesia and Analgesia·C L Wu, L A Fleisher
Jul 3, 2002·Pediatrics·UNKNOWN Surgical Advisory Panel. American Academy of Pediatrics
Mar 1, 1958·Anesthesiology·L W FABIANC R STEPHEN
Jul 1, 1964·Anesthesia and Analgesia·T D GRAFFE KELLEY
Oct 1, 2003·Journal of Anesthesia·Yasuo KawashimaShuji Dohi
Jun 3, 2004·European Heart Journal·P FribergS Mårild
Jun 17, 2004·JAMA : the Journal of the American Medical Association·Allison A HedleyKatherine M Flegal

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Citations

Sep 3, 2013·Neurotoxicology·Xiaofeng ShenFuzhou Wang
Sep 14, 2015·Revista brasileira de anestesiologia·Dora CatréAntónio Silvério Cabrita
Sep 2, 2015·Brazilian Journal of Anesthesiology·Dora CatréAntónio Silvério Cabrita
Mar 1, 2015·Burns : Journal of the International Society for Burn Injuries·Sarah J WarwickerAmber E Young
Jan 5, 2019·Pediatric Surgery International·Daniel A ReichBrendan T Campbell
Sep 24, 2019·Anesthesia Progress·Alia El-MowafyDaniel A Haas

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