Improved outcomes with European Society of Cardiology guideline-adherent antithrombotic treatment in high-risk patients with atrial fibrillation: a report from the EORP-AF General Pilot Registry

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Gregory Y H LipGiuseppe Boriani

Abstract

Guideline-adherent therapy for stroke prevention in atrial fibrillation has been associated with better outcomes, in terms of thromboembolism (TE) and bleeding. In this report from the EuroObservational Research Programme-Atrial Fibrillation (EORP-AF) Pilot General Registry, we describe the associated baseline features of 'high risk' AF patients in relation to guideline-adherent antithrombotic treatment, i.e. whether they were adherent, over-treated, or under-treated based on the 2012 European Society of Cardiology (ESC) guidelines. Secondly, we assessed the predictors of guideline-adherent antithrombotic treatment. Thirdly, we evaluated outcomes for all-cause mortality, TE, bleeding, and the composite endpoint of 'any TE, cardiovascular death or bleeding' in relation to whether they were ESC guideline-adherent treatment. From the EORP-AF cohort, the follow-up dataset of 2634 subjects was used to assess the impact of guideline adherence or non-adherence. Of these, 1602 (60.6%) were guideline adherent, whilst 458 (17.3%) were under-treated, and 574 (21.7%) were over-treated. Non-guideline-adherent treatment can be related to region of Europe as well as associated clinical features, but not age, AF type, symptoms, or echocardiogr...Continue Reading

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Dec 12, 2013·Thrombosis and Haemostasis·Gregory Y H LipSalim Yusuf
Dec 18, 2013·The American Journal of Cardiology·Gregory Y H LipUNKNOWN RHYTHM-AF Scientific Committee
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Citations

Oct 21, 2015·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Paulus KirchhofA John Camm
Feb 24, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Antonio Hernández MadridCarina Blomstrom-Lundqvist
May 14, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Marco ProiettiUNKNOWN Belgian Heart Rhythm Week Investigators
May 14, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Stefano FumagalliNikolaos Dagres
May 20, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Marco ProiettiUNKNOWN AF Gen Pilot Investigators
May 23, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Xue LiEsther W Chan
Oct 23, 2016·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Marco ProiettiUNKNOWN REPOSI investigators
Jun 12, 2016·International Journal of Clinical Pharmacy·Yishen Wang, Beata Bajorek
Aug 28, 2016·European Heart Journal·Paulus KirchhofUNKNOWN ESC Scientific Document Group
Nov 4, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Paulus KirchhofKatja Zeppenfeld
Sep 25, 2016·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Paulus KirchhofKatja Zeppenfeld
Oct 18, 2016·The American Journal of Medicine·Michał MazurekGregory Y H Lip
Mar 24, 2017·Thrombosis and Haemostasis·José Miguel Rivera-CaravacaFrancisco Marín
Jul 6, 2017·Expert Opinion on Drug Safety·José Miguel Rivera-CaravacaGregory Y H Lip
Oct 11, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Giuseppe BorianiUNKNOWN Steering Committee (National Coordinators)
Oct 19, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Dipak KotechaUNKNOWN European Society of Cardiology (ESC) Atrial Fibrillation Guidelines Taskforce, the CATCH ME consortium and the European Hear
Jan 19, 2018·Journal of Cardiovascular Electrophysiology·Giuseppe BorianiUNKNOWN EORP-AF General Pilot Registry Investigators
Feb 13, 2018·International Journal of Clinical Practice·José Miguel Rivera-CaravacaGregory Y H Lip
Jun 3, 2017·Heart·Andrea IsaewTom Marshall
Nov 17, 2017·Circulation. Arrhythmia and Electrophysiology·Lorne J GulaAllan C Skanes
Jul 7, 2017·Stroke; a Journal of Cerebral Circulation·Michał MazurekGregory Y H Lip
Apr 11, 2018·Cardiology in Review·C J G M HoornL R C Dekker
Dec 13, 2018·Journal of Cardiovascular Medicine·Raffaele De CaterinaUNKNOWN ETNA-AF-Europe investigators
Mar 16, 2019·JAMA : the Journal of the American Medical Association·Alexander C FanaroffRenato D Lopes
Apr 6, 2019·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·M S JacobsR G Tieleman
Oct 5, 2019·European Journal of Preventive Cardiology·Marco ProiettiGiuseppe Boriani
May 12, 2020·Stroke; a Journal of Cerebral Circulation·Rungroj KrittayaphongUNKNOWN COOL-AF Investigators
Jun 10, 2020·International Journal of Environmental Research and Public Health·Ştefan Cristian VesaAnca Dana Buzoianu
Jun 15, 2020·European Journal of Clinical Investigation·Lorenzo FalsettiAlessandro Capucci
Aug 4, 2020·International Journal of Clinical Practice·José Miguel Rivera-CaravacaFrancisco Marín
Aug 30, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Elena ArbeloMario Martins Oliveira
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Aug 26, 2016·Journal of Thrombosis and Haemostasis : JTH·G Y H Lip
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