Improved parameterization of the transcranial Doppler signal

Ultrasound in Medicine & Biology
A Schaafsma

Abstract

The great potential of transcranial Doppler (TCD) as a tool for neuromonitoring is limited by the current parameterization of the signal. This article proposes a set of new parameters that more accurately represents the shape of the waveform and eliminates a number of confounding factors. This set of parameters was tested in 227 patients with ipsilateral carotid artery stenosis and compared with 31 normal subjects recruited at our laboratory. From the TCD waveform, we calculated on a beat-to-beat basis the maximal change in flow velocity at stroke onset (acceleration or acc), the maximal flow velocity during the first 100 ms of systole (sys1) and the maximal flow velocity in the remaining part of systole (sys2). All data were normalized relative to the mean diastolic flow velocity over an interval ranging from 520 till 600 ms after stroke onset (dias@560). For the group with carotid stenosis compared with the normal controls the average ± SD for acc (20.2 ± 9.5 vs. 20.2 ± 6.7; p = 0.98) and sys1 (1.82 ± 0.38 vs. 1.77 ± 0.56; p = 0.35) did not differ significantly. The average ±SD for sys2 (1.94 ± 0.33 vs. 1.50 ± 0.12; p < 0.001), however, was significantly higher in the group with carotid stenosis than in the group of normal su...Continue Reading

Associated Clinical Trials

Jun 12, 2020·Sergio Brasil, MD

References

May 16, 2000·Neurosurgical Review·N G RainovW Burkert
Dec 26, 2001·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·A SchaafsmaJ P M Vos
Sep 6, 2007·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Tokihisa NagaiKatsuhiko Kohara
Jul 9, 2010·Annals of Biomedical Engineering·Taous-Meriem Laleg-KiratiAndry Van de Louw

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Citations

Nov 24, 2020·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Amber Y DornRobert B Hamilton
Apr 9, 2021·The Journal of Cardiovascular Surgery·Mirte SchaafsmaArjen Schaafsma

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