Improved physical performance as a therapeutic objective in patients with angina

British Journal of Clinical Pharmacology
A S Ling, J T Groel

Abstract

1 Improvement in physical performance, based on exercise tolerance, self-assessed work and physician-rated functional capacities, is proposed as a measure of efficacy of anti-anginal therapy in the rehabilitation of the cardiac patient. 2 Improved physical performance parallels changes in frequency of anginal attacks and a nitroglycerin requirements following beta-blocker therapy. 3 Nadolol (a beta-blocker), given once daily is as effective as propranolol, given four times daily as an anti-anginal agent.

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Related Concepts

Adrenergic beta-Antagonists
Angina Pectoris
Drug Evaluation
Propanolamines
Rexigen
Work Capacity Evaluation

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