Feb 28, 2020

Improved reference genome of the arboviral vector Aedes albopictus

bioRxiv
Umberto PalatiniMariangela Bonizzoni

Abstract

The Asian tiger mosquito Aedes albopictus is globally expanding and has become the main vector for human arboviruses in Europe. Here we present AalbF2, a dramatically improved assembly of the Ae. albopictus genome that has revealed widespread viral insertions, novel microRNAs and piRNA clusters, the sex determining locus, new immunity genes, and has enabled genome-wide studies of geographically diverse Ae. albopictus populations and analyses of the developmental and stage-dependent network of expression data. Additionally, we built the first physical map for this species with 75% of the assembled genome anchored to the chromosomes. These up-to-date resources of the genome provide a foundation to improve understanding of the adaptation potential and the epidemiological relevance of this species and foster the development of innovative control measures.

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Mentioned in this Paper

Species
HIV Viral Load
Aedes albopictus
Genome
Piwi-Interacting RNA
Chromosomes
Genetic Vectors
Biological Neural Networks
Widespread
Locus

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