PMID: 9178230Jun 1, 1997Paper

Improved sensitivity to overlapping multiplet signals in in vivo proton spectroscopy using a multiecho volume selective (CPRESS) experiment

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
J HennigO Speck

Abstract

A method for volume selective proton spectroscopy is presented based on a multiecho sequence with short refocusing interval tcp. It is demonstrated, that by appropriate choice of tcp on the order of 4-6 ms, signals from overlapping multiplets like the glutamine and glutamate (Glu/Gln) resonances in spectra of the human brain are considerably increased compared with a conventional PRESS volume selection scheme. Thus proton spectra from J-coupled multiplet signals can be acquired with TE on the order of 20-30 ms avoiding the baseline problems arising at shorter echo times due to broad resonances. This allows to selectively acquire spectra from substances with longer T2 without the confounding effects from J-coupling occurring in conventional volume selection techniques.

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Citations

Nov 7, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·W Dreher, D Leibfritz
Jan 17, 2004·Magnetic Resonance Imaging·Andreas H TrabesingerPeter Boesiger
Jul 20, 2011·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Sarah BiedermannAlexander Sartorius
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Apr 22, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Charles H CunninghamJohn M Pauly
Nov 14, 2008·NMR in Biomedicine·Ileana Hancu
Oct 27, 2009·Journal of Magnetic Resonance Imaging : JMRI·Ileana Hancu
Jul 22, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J W PanH P Hetherington
Jan 18, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Dinesh Kumar DeelchandMałgorzata Marjańska
May 19, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ileana HancuEarl A Zimmerman
Jan 26, 2011·NMR in Biomedicine·Ileana Hancu, John Port
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May 21, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Brian J SoherAndrew A Maudsley
Oct 25, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·L HofmannR Kreis
Nov 10, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Zepeng WangFan Lam

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