PMID: 11061053Nov 4, 2000

Improved survival after acute myocardial infarction in patients with advanced Killip class

Clinical Cardiology
W L MillerS L Kopecky


The continuing applicability of the Killip classification system to the effective stratification of long-term and short-term outcome in patients with acute myocardial infarction (MI) and its influence on treatment strategy calls for reanalysis in the setting of today's primary reperfusion treatments. Our study sought to test the hypothesis that Killip classification, established on admission in patients with acute MI, is an effective tool for early prediction of in-hospital mortality and long-term survival. A series of 909 consecutive Olmsted County patients admitted with acute MI to St. Marys Hospital, Mayo Clinic, between January 1988 and March 1998 was analyzed. Killip classification was the primary variable. Endpoints were in-hospital death, major in-hospital complications, and post-hospital death. Patients analyzed included 714 classified as Killip I, 170 classified as Killip II/III, and 25 classified as Killip IV. Increases in in-hospital mortality and prevalence of in-hospital complications correspond significantly with advanced Killip class (p < 0.01), with in-hospital mortality 7% in class I, 17.6% in classes II/III, and 36% in class IV patients (p < 0.001). Killip classification was strongly associated with mode of th...Continue Reading


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Mar 24, 2005·The American Heart Hospital Journal·W H Wilson Tang, Gary S Francis
Sep 10, 2020·Frontiers in Cardiovascular Medicine·Jianhua YaoJiahong Xu


Mar 11, 1992·Journal of the American College of Cardiology·M D HibbardB J Gersh
Mar 1, 1991·Journal of the American College of Cardiology·L LeeW W O'Neill
Feb 1, 1988·The American Journal of Cardiology·C DuboisH E Kulbertus
Feb 8, 1969·Lancet·R M NorrisP J Scott
Feb 1, 1973·British Heart Journal·B L Chapman, C H Gray
Dec 1, 1970·The American Journal of Cardiology·S ScheidtT Killip
Oct 1, 1967·The American Journal of Cardiology·T Killip, J T Kimball
Jul 1, 1984·American Heart Journal·R F GillumT E Kottke
Feb 15, 1994·The American Journal of Cardiology·J S JenkinsG F Petroski
Dec 24, 1997·JAMA : the Journal of the American Medical Association·W D WeaverF Ribichini
May 23, 1998·The New England Journal of Medicine·Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS)
Jun 19, 1998·Clinical Cardiology·D L DriesB J Gersh
Aug 26, 1998·The New England Journal of Medicine·S S GottliebR A Vogel

Related Concepts

Survival Analysis
Logistic Regression
Myocardial Infarction
Hospital Mortality
Acute Disease
Bikinia le-testui
X-Linked Combined Immunodeficiency Diseases
Physiological Reperfusion
Cox Proportional Hazards Models

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