Improved survival for melanoma in Northern Ireland: a comparison of two 5-year periods (1984-88 and 1994-98)

The British Journal of Dermatology
E A McMullenO M Dolan

Abstract

The incidence of cutaneous malignant melanoma has been rising steadily in Caucasian populations for several decades, with a doubling time of 10-14 years. An increase in incidence of about 5% per year has been reported in most Caucasian populations since the early 1960s. This study was designed to determine the changing incidence of primary cutaneous malignant melanoma in Northern Ireland and to examine changes in survival rates from cutaneous malignant melanoma in two 5-year periods, 1984-88 and 1994-98. One thousand three hundred and twenty-six patients with invasive primary cutaneous melanoma were included in the study. The age standardized rate of melanoma rose from 4.3 per 100,000 population per year in men and 8.6 per 100,000 population per year in women to 7.7 and 11.8, respectively, per 100,000 population per year in the 1994-98 period. Overall, the absolute 5-year survival for the 1984-88 period was 71.0% [95% confidence interval (CI) 66.9-75.1%] and 77.4% (95% CI 73.4-81.4%) for the 1994-98 period. Women consistently showed better survival at all ages and within almost all categories of thickness of primary tumour. Younger patients of both sexes showed better survival rates. When survival rates between the 1984-88 and ...Continue Reading

References

Jan 1, 1992·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Nov 1, 1991·Cancer Causes & Control : CCC·T M Mack, B Floderus
May 4, 1996·BMJ : British Medical Journal·G G GilesV J Thursfield
May 1, 1997·The British Journal of Dermatology·J G Miller, S Mac Neil
Jan 1, 1997·British Journal of Cancer·P J PedlowW S Lowry
Mar 10, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J A SmithJ C Redburn
Dec 22, 1999·Archives of Dermatology·D M LipskerB J Cribier

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Citations

Apr 21, 2009·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Anthony MontellaMathieu Boniol
Nov 8, 2006·Journal of the American Geriatrics Society·Carlos A Reyes-OrtizYong-Fang Kuo
Jun 29, 2007·The British Journal of Dermatology·D LipskerG Hedelin
Aug 24, 2007·Journal of the European Academy of Dermatology and Venereology : JEADV·E A McMullenF Kee
Aug 23, 2006·Journal of the European Academy of Dermatology and Venereology : JEADV·S AquilinaL Scerri

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