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Improved vectors and genome-wide libraries for CRISPR screening

bioRxiv

Jun 28, 2014

Neville E. SanjanaFeng Zhang

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Abstract

Genome-wide, targeted loss-of-function pooled screens using the CRISPR (clustered regularly interspaced short palindrome repeats)?associated nuclease Cas9 in human and mouse cells provide an alternative screening system to RNA interference (RNAi). Initial lentiviral delivery systems for...read more

Mentioned in this Paper

Knock-out
Gecko
Cloning Vectors
Nuclease
Clustered Regularly Interspaced Short Palindromic Repeats
RNA Interference
19
16
Paper Details
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  • Improved vectors and genome-wide libraries for CRISPR screening

    bioRxiv

    Jun 28, 2014

    Neville E. SanjanaFeng Zhang

    PMID: 990006726

    DOI: 10.1101/006726

    Abstract

    Genome-wide, targeted loss-of-function pooled screens using the CRISPR (clustered regularly interspaced short palindrome repeats)?associated nuclease Cas9 in human and mouse cells provide an alternative screening system to RNA interference (RNAi). Initial lentiviral delivery systems for...read more

    Mentioned in this Paper

    Knock-out
    Gecko
    Cloning Vectors
    Nuclease
    Clustered Regularly Interspaced Short Palindromic Repeats
    19
    16
    Paper Details
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