Improvement of adult Still's disease with granulocyte and monocyte adsorption apheresis

Clinical and Experimental Dermatology
T KanekuraTamotsu Kanzaki

Abstract

Adult Still's disease is characterized by a high spiking fever, transient skin rash, and polyarthralgia. Joint pain is one of the major complaints and is often intractable. We assessed the efficacy of granulocyte and monocyte adsorption apheresis (GCAP) therapy for treating arthralgia in adult Still's disease. A 33-year-old woman with adult Still's disease who suffered from recalcitrant arthralgia resistant to systemic corticosteroids was treated with GCAP therapy. She underwent five GCAP treatments at 5-day intervals. Her joint pain responded dramatically to the GCAP therapy, suggesting that GCAP may be useful for treating adult Still's disease. We present a detailed description of the patient and this novel therapy.

References

Mar 1, 1971·Annals of the Rheumatic Diseases·E G Bywaters
Jul 26, 2002·Journal of the American Academy of Dermatology·Takuro KanekuraTamotsu Kanzaki
Aug 2, 2003·Journal of the American Academy of Dermatology·Takuro KanekuraTamotsu Kanzaki
Jan 17, 2004·Journal of the American Academy of Dermatology·Takuro KanekuraTamotsu Kanzaki
Jan 20, 2004·Dermatology : International Journal for Clinical and Investigative Dermatology·Takuro KanekuraTamotsu Kanzaki

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Citations

Jan 17, 2004·Journal of the American Academy of Dermatology·Takuro KanekuraTamotsu Kanzaki
Aug 4, 2005·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Takuro KanekuraTamotsu Kanzaki
Jul 5, 2006·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Takuro KanekuraTamotsu Kanzaki
Jul 5, 2006·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Takuro KanekuraTamotsu Kanzaki
Oct 11, 2013·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Masanao SakanoueTakuro Kanekura
Sep 3, 2011·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Tomomi FujisawaMariko Seishima
Oct 20, 2011·The Journal of Dermatology·Ryoko ShukuyaShigaku Ikeda

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Adult-Onset Still's Disease

Adult-onset Still's disease (AOSD) is a form of Still's disease, a rare systemic autoinflammatory disease characterized by the classic triad of persistent high spiking fevers, joint pain, and a distinctive salmon-colored bumpy rash. Discover the latest research on AOSD here.

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