PMID: 2480101May 1, 1989Paper

[Improvement of airway hyperreactivity in bronchial asthma patients with short disease duration treated with anti-allergic agents].

Arerugī = [Allergy]
K HoshinoS Yano

Abstract

We treated bronchial asthma patients with anti-allergic agents for more than three months, and examined their effects on the airway hyperreactivity in 15 cases; five were short cases (disease duration was less than one year from the onset) and 10 were long cases (disease duration was more than one year). A significant improvement in airway hyperreactivity to histamine inhalation was observed in all five short cases. In 4 out of 5 short cases, the threshold of histamine concentration reached to the normal level of 10,000 micrograms/ml. On the other hand, the significant improvement was observed only in 2 out of 10 cases. We suggested that in "short asthma cases" the airway hyperreactivity could improve with the use of anti-allergic agents in a relatively short period and at a high rate.

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