Improvement of human T-lymphotropic virus type 1 associated demyelinating neuropathy with corticosteroid therapy

Rinshō shinkeigaku = Clinical neurology
Masayoshi YamamotoToshiaki Hamano

Abstract

The patient was a 58-year-old man, who was hospitalized with progressive bilateral leg weakness, and sensory impairment in all four extremities. Chronic inflammatory demyelinating polyneuropathy (CIDP) was suspected based on an electrophysiological examination, and intravenous immunoglobulin therapy (IVIg) was initiated. However, his symptoms progressed. The serum and cerebrospinal fluid were positive for human T-lymphotropic virus type 1 (HTLV-1) antibodies; hence the patient was diagnosed as having HTLV-1 associated neuropathy. After administration of corticosteroid, muscle strength markedly improved. Thus, our findings suggest that rather than IVIg, corticosteroid therapy is recommended for the treatment of CIDP like neuropathy in HTLV-1 infected patients.

References

Apr 1, 1990·Journal of Neurology, Neurosurgery, and Psychiatry·K ArakawaH Itoh
Mar 15, 2006·The Neurologist·Hideaki MatsuiNobuyuki Oka
Jun 21, 2016·Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology·Natsumi ArayaYoshihisa Yamano

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.