Improvement of left ventricular myocardial short-axis, but not long-axis function or torsion after cardiac resynchronisation therapy: an assessment by two-dimensional speckle tracking

Heart
Qing ZhangC-M Yu

Abstract

To evaluate whether short-axis function plays a part in determining left ventricular (LV) geometric and functional improvement after cardiac resynchronisation therapy (CRT). 39 patients who received CRT were enrolled. 2D speckle tracking echocardiography was performed at baseline and three months after CRT to assess mean systolic circumferential (epsilon-circum), radial (epsilon-radial) and longitudinal (epsilon-long) strain and torsion. Responders of reverse remodelling (n = 21) had higher baseline mean epsilon-circum than non-responders (p<0.05), who also had improvement in mean epsilon-circum and mean epsilon-radial (both p<0.05) after CRT. Also, the increase in mean epsilon-circum correlated with increase in ejection fraction (r = 0.57, p<0.001) and decrease in mid-cavity width (r = -0.52, p = 0.001). A baseline mean epsilon-circum of >or=6.5% predicted a gain in ejection fraction >or=5%, with a sensitivity of 73% and a specificity of 71%. The baseline epsilon-long was not different between the two groups, and remained unchanged after CRT. The torsion did not improve in responders, but was worsened in non-responders (p<0.05). The improvement of LV short-axis function but not long-axis function or torsion contributes to the ...Continue Reading

Associated Clinical Trials

Citations

May 13, 2011·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·I K Rüssel, M J W Götte
Jan 20, 2010·JACC. Cardiovascular Imaging·Matteo BertiniJeroen J Bax
Jul 12, 2012·European Heart Journal Cardiovascular Imaging·Cheuk-Man Yu, Fang Fang
Jun 26, 2012·BMC Cardiovascular Disorders·Aaron A PhillipsDarren E R Warburton
Jul 26, 2012·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Alistair A Young, Brett R Cowan
Apr 18, 2009·Future Cardiology·Andrew J Yoon, Jonathan N Bella
Jul 13, 2013·Heart·Cheuk-Man Yu, Fang Fang
Oct 17, 2014·Expert Review of Cardiovascular Therapy·Parash PokharelJonathan N Bella
Jul 15, 2015·European Heart Journal Cardiovascular Imaging·Nina E HasselbergThor Edvardsen
Sep 5, 2015·Pediatric Cardiology·Sok-Leng KangBeverly Tsai-Goodman
Mar 10, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Takeshi MaruoKazutaka Aonuma
Jul 31, 2013·The Journal of Surgical Research·Alice WangHenry M Spotnitz
Jun 27, 2015·Journal of Magnetic Resonance Imaging : JMRI·Johannes T KowallickAndreas Schuster
Jun 9, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Victoria DelgadoJeroen J Bax
Mar 13, 2016·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Sandra HamadaMichael Becker
Jun 12, 2012·Clinical Physiology and Functional Imaging·Cinzia ValzaniaMaria J Eriksson
Jun 5, 2013·Journal of Veterinary Internal Medicine·N E ZoisL H Olsen
Mar 31, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Anne BernardAlfredo Hernandez
Apr 10, 2009·JACC. Cardiovascular Imaging·Partho P SenguptaBijoy K Khandheria
Nov 20, 2010·Journal of the American College of Cardiology·Chung-Lieh HungUNKNOWN VALIANT investigators
May 23, 2009·Journal of the American College of Cardiology·John E Sanderson
Sep 26, 2009·Journal of the American College of Cardiology·Matteo BertiniJeroen J Bax
Oct 14, 2014·Journal of cardiovascular ultrasound·Hui-Jeong HwangIl Suk Sohn
Apr 27, 2016·Journal of Cardiovascular Medicine·Alessandro Paoletti PeriniLuigi Padeletti
Jun 15, 2010·The Journal of Thoracic and Cardiovascular Surgery·Toshinobu KazuiHitoshi Okabayashi
Aug 16, 2016·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Hang ZhaoBen He
Dec 21, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Chiara SartoriPaolo Nicola Marino
Nov 23, 2010·Journal of Applied Physiology·Corey R TomczakMark J Haykowsky
Nov 8, 2008·Journal of Applied Physiology·Ben T Esch, Darren E R Warburton
Apr 23, 2020·Heart Failure Reviews·Alfred StanleyGerald Buckberg
Dec 18, 2018·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Inna Y GongAndrew T Yan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.