Improvement of prearterialized venous flap survival with delay procedure in rats

Journal of Reconstructive Microsurgery
Hede YanFeng Zhang

Abstract

The purpose of this experimental study is to investigate the improvement in flap survival of prearterialization with delay procedure in venous flaps in rats. The transverse superficial inferior epigastric flap was utilized. Forty-six rats were randomized into four groups: group 1 as arterialized venous flaps, group 2 as venous flaps of prearterialization with delay procedure, group 3 as arterial perfusion venous flap, and group 4 as venous perfusion venous flap. Direct observation, histological analysis, and vascular perfusion examination by Indian ink injection were performed for flap assessment. The percentage of flap survival was 41.6 +/- 2.4%, 98.0 +/- 1.8%, 89.5 +/- 1.0%, and 11.3 +/- 0.8% in these four groups, respectively. Significant differences were noted between groups ( P < 0.05) except for between group 2 and group 3 ( P > 0.05). Vascular perfusion studies revealed that the Indian ink filled the entire flaps of group 2 in comparison with partially filled flaps in other groups. Histological examination showed more small vessels were observed through all layers of the flaps as well as dilated superficial veins in group 2 than those in other groups. In conclusion, prearterialization with delay procedure can improve the...Continue Reading

Citations

Aug 30, 2013·Plastic and Reconstructive Surgery·Hede YanWeiyang Gao
Aug 1, 2013·Plastic and Reconstructive Surgery. Global Open·Martín IglesiasMelina Díaz-Morales
Apr 30, 2019·Plastic and Reconstructive Surgery·Diogo CasalJoão Goyri-O'Neill
Jan 29, 2019·Journal of Plastic Surgery and Hand Surgery·Bin ZhaoHede Yan

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