PMID: 11906576Mar 22, 2002Paper

Improvement of symptoms in infant colic following reduction of lactose load with lactase

Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association
D KanabarP Clayton

Abstract

Transient lactose intolerance has been identified as a possible causative factor in infant colic. A double-blind randomised placebo-controlled crossover study to investigate this has been undertaken in 53 babies with symptoms of colic. Pre-incubation of the feed with lactase resulted in breath hydrogen levels and total crying time which were both at least 45% lower than figures with placebo treatment, in 26% of the full trial group (95% confidence interval 12.9% to 44.4%), and in 38% of compliers (95% confidence interval 18.8% to 59.4%). The remainder did not respond to the same extent. These findings suggest that infant colic may have a multiple aetiology, and that in a significant number of cases the immediate cause is transient lactose intolerance, in which cases pretreatment of feeds with lactase can result in considerable symptomatic benefits.

References

Dec 1, 1991·Pediatric Clinics of North America·A R Miller, R G Barr
Aug 1, 1990·The Journal of Pediatrics·J J MillerJ C Brand
May 1, 1989·Archives of Disease in Childhood·J J MillerJ C Brand
Oct 1, 1989·The Journal of Pediatrics·J S HyamsW R Treem
Dec 1, 1988·The Journal of Pediatrics·D J MooreG P Davidson
May 1, 1985·Acta paediatrica Scandinavica·B Danielsson, C P Hwang
Jul 17, 1969·The New England Journal of Medicine·M D Levitt
Feb 20, 1981·JAMA : the Journal of the American Medical Association·W M Liebman

❮ Previous
Next ❯

Citations

Oct 7, 2009·Applied Microbiology and Biotechnology·Shane O'Connell, Gary Walsh
Apr 8, 2011·Journal of Paediatrics and Child Health·Belinda HallAnske Robinson
May 7, 2011·World Journal of Gastroenterology : WJG·Dámaso InfanteBernard Le Luyer
Sep 27, 2014·Nutrients·Bert J M van de HeijningOlivier Goulet
Mar 1, 2012·La Presse médicale·Virginie Bruyas-BertholonLaurent Letrilliart
Oct 24, 2007·Emergency Medicine Clinics of North America·Martin Herman, Audrey Le
Aug 28, 2007·Acta Paediatrica·Francesco Savino
Jan 1, 2014·Journal of Paediatrics and Child Health·Romi Rimer, Harriet Hiscock
Dec 15, 2004·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·P RoyC Gontier
May 2, 2006·Complementary Therapies in Clinical Practice·Clive Hayden, Brenda Mullinger
Aug 7, 2013·The Journal of Pediatrics·Carlos Lifschitz
Jan 25, 2017·Journal of Comparative Effectiveness Research·Yvan VandenplasMihai Manolache
Mar 12, 2015·Clinical Pediatrics·Pamela L CekolaJosé M Saavedra
Jun 10, 2015·Clinical Pediatrics·Peter F BelamarichAndrew D Racine
Sep 16, 2016·The Cochrane Database of Systematic Reviews·Elena BiagioliFrancesco Savino
Dec 14, 2012·The Cochrane Database of Systematic Reviews·Dawn DobsonGeorge Lewith
Oct 12, 2018·The Cochrane Database of Systematic Reviews·Morris GordonFrancesco Savino
Mar 14, 2019·The Cochrane Database of Systematic Reviews·Teck Guan OngAnthony K Akobeng
May 4, 2006·Current Opinion in Allergy and Clinical Immunology·Ralf G Heine
Dec 15, 2015·Journal of Pediatric Gastroenterology and Nutrition·Tracy HarbRebecca Hill
Jan 17, 2020·Alimentary Pharmacology & Therapeutics·Rita NocerinoRoberto Berni Canani
Oct 16, 2016·Pediatric Gastroenterology, Hepatology & Nutrition·Yvan VandenplasMaroun Sokhn
Mar 1, 2012·Infant Mental Health Journal·Amy L SalisburyBarry Lester
May 16, 2018·Nature Reviews. Gastroenterology & Hepatology·Judith ZeevenhoovenMarc A Benninga
Feb 9, 2005·The American Journal of Clinical Nutrition·Robert J ShulmanE O'Brian Smith
Jul 22, 2017·Pediatric Gastroenterology, Hepatology & Nutrition·Ioannis XiniasYvan Vandenplas
Oct 3, 2018·F1000Research·Siel DaelemansYvan Vandenplas
Feb 8, 2003·British Journal of Community Nursing·Claire Swadling, Peter Griffiths
Jan 27, 2016·The South African Journal of Communication Disorders. Die Suid-Afrikaanse Tydskrif Vir Kommunikasieafwykings·Hanlie Degenaar, Alta Kritzinger
Nov 2, 2004·The Medical Journal of Australia·Harriet Hiscock, Brigid Jordan
Nov 3, 2010·The Medical Journal of Australia·Pamela S Douglas, Harriet Hiscock
Jul 1, 2020·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Rossella TurcoAnnamaria Staiano
Jan 1, 2005·Infant Mental Health Journal·Aimee E MaxtedBarry M Lester

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.