Improvement of the bone-screw interface strength with hydroxyapatite-coated and titanium-coated AO/ASIF cortical screws

Journal of Orthopaedic Trauma
A MoroniS Giannini

Abstract

To evaluate whether coating AO/ASIF screws with osteoconductive materials can improve bone-screw fixation. Ninety-six AO/ASIF 4.5-millimeter cortical screws were divided into four paired groups and implanted in the femurs and tibiae of six sheep: Group A = standard stainless steel screws; Group B = stainless steel screws coated with highly crystalline hydroxyapatite; Group C = stainless steel screws coated with low crystalline hydroxyapatite; Group D = titanium screws coated with titanium. The screws were implanted according to the standard AO technique to an insertion torque of 2,000 Newton-millimeters. Sheep were killed at one, three, and twelve months after surgery. Extraction torque was measured on six screws from each group selected at random at time of each euthanization. Morphologic analysis of the bone-screw interface was performed on the remaining screws. At each euthanization the extraction torque of Group A was lower than that of the other groups (p < 0.0001). At three and twelve months the extraction torque of Group B was higher than that of Group D (p = 0.002). Morphologic results showed extensive bone-screw gap in Group A. Optimal osteointegration was observed in Groups B and C. Osteointegration of Group D was hig...Continue Reading

References

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Citations

Jun 21, 2005·Journal of Materials Science. Materials in Medicine·M CimermanM Tonin
Dec 5, 2008·Revue de chirurgie orthopédique et réparatrice de l'appareil moteur·J-M FéronJ Puget
Jul 16, 2008·Journal of Neuroscience Methods·Helen Sherk, Elizabeth J Wilkinson
Apr 14, 2007·Clinics in Podiatric Medicine and Surgery·Jonathan M Labovitz, Kate Revill
Mar 27, 2009·Journal of Biomedical Materials Research. Part a·Xiupeng WangAyako Oyane
Sep 28, 2004·Journal of Orthopaedic Trauma·Karl StoffelMarkus Kuster
Jun 7, 2017·Orthopedics·Takahiro IwataHaruhiko Akiyama
Jan 8, 2008·Journal of Orthopaedic Trauma·Antonio MoroniBurkhardt Wippermann
Mar 30, 2005·Journal of Orthopaedic Trauma·H David MoehringStephen R Lindholm
Jun 18, 2019·The Journal of the American Academy of Orthopaedic Surgeons·Geoffrey Marecek, Hugo Centomo
Mar 5, 2003·Clinical Orthopaedics and Related Research·Antonio MoroniBurkhard Wippermann
May 1, 2004·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·A MoroniS Giannini
Aug 5, 2004·Clinical Orthopaedics and Related Research·Antonio MoroniSandro Giannini
May 6, 2006·The Journal of the American Academy of Orthopaedic Surgeons·Nirmal C TejwaniPramod Achan
Oct 31, 2007·The Journal of Bone and Joint Surgery. American Volume·S GianniniR Bevoni
Nov 17, 2016·Journal of Children's Orthopaedics·Dimitri CeroniEleftheria Samara

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