PMID: 15348050Sep 7, 2004Paper

Improvement of titanium alloy for biomedical applications by nitriding and carbonitriding processes under glow discharge conditions

Journal of Materials Science. Materials in Medicine
E CzarnowskaE Karczmarewicz

Abstract

Although titanium alloys are used in medicine, they present low wear resistance. In this paper we present the results of studies on surface layers produced by nitriding at three different temperatures, and by carbonitriding under glow discharge conditions in order to improve wear resistance, hardness, and to modulate microstructure and chemical composition of surface layers. A cell culture model using human fibroblasts was chosen to study the effect of such treatments on the cytocompatibility of these materials. The results showed that nitrided and carbonitrided surface layers were cytocompatible. Modulation of surface microstructure by temperature in the nitriding process and chemical composition of surface layers by carbonitriding led to differences in cellular behaviour. Cell proliferation appeared to be slightly reduced from the 6th day of culture on nitrided surfaces produced at 730 degrees C and 1000 degrees C, however after 12 days of culture, the best growth was on surface layers produced at 850 degrees C. The best viability was observed on the carbonitrided layer. The orientation and shape of the cells corresponded to surface topography. Nitriding and carbonitriding under glow discharge conditions may constitute intere...Continue Reading

Citations

Feb 3, 2011·Medical & Biological Engineering & Computing·Haw-Ming HuangWei-Jen Chang
Aug 23, 2008·Dental Materials Journal·Wei-Jen ChangHaw-Ming Huang
Apr 30, 2013·Journal of Biomedical Materials Research. Part a·Emanuela P FerrazAdalberto L Rosa
Jul 2, 2016·BioMed Research International·Yu-Chi ChangWei-Jen Chang

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