Improvement of uncorrected visual acuity and contrast sensitivity with perceptual learning and transcranial random noise stimulation in individuals with mild myopia

Frontiers in Psychology
Rebecca CamilleriGianluca Campana


Perceptual learning has been shown to produce an improvement of visual acuity (VA) and contrast sensitivity (CS) both in subjects with amblyopia and refractive defects such as myopia or presbyopia. Transcranial random noise stimulation (tRNS) has proven to be efficacious in accelerating neural plasticity and boosting perceptual learning in healthy participants. In this study, we investigated whether a short behavioral training regime using a contrast detection task combined with online tRNS was as effective in improving visual functions in participants with mild myopia compared to a 2-month behavioral training regime without tRNS (Camilleri et al., 2014). After 2 weeks of perceptual training in combination with tRNS, participants showed an improvement of 0.15 LogMAR in uncorrected VA (UCVA) that was comparable with that obtained after 8 weeks of training with no tRNS, and an improvement in uncorrected CS (UCCS) at various spatial frequencies (whereas no UCCS improvement was seen after 8 weeks of training with no tRNS). On the other hand, a control group that trained for 2 weeks without stimulation did not show any significant UCVA or UCCS improvement. These results suggest that the combination of behavioral and neuromodulatory ...Continue Reading


May 15, 1992·Science·T PoggioS Edelman
Jun 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·A Karni, Dov Sagi
Feb 1, 1971·The Journal of the Acoustical Society of America·H Levitt
Jan 1, 1996·Optometry and Vision Science : Official Publication of the American Academy of Optometry·M Bach
Mar 1, 1997·Vision Research·U PolatA M Norcia
Jan 1, 1997·Spatial Vision·D H Brainard
Apr 18, 2000·Vision Research·Z Liu, D Weinshall
Oct 5, 2001·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·M BachG Kommerell
Jan 9, 2004·Perception & Psychophysics·Gianluca Campana, Clara Casco
Apr 21, 2004·Proceedings of the National Academy of Sciences of the United States of America·U PolatDov Sagi
Sep 29, 2004·Trends in Cognitive Sciences·Merav Ahissar, Shaul Hochstein
Oct 14, 2005·Nature Neuroscience·Shu-Guang KuaiCong Yu
Dec 18, 2007·Vision Research·Gilles PourtoisSophie Schwartz
Dec 21, 2007·PloS One·Ben S WebbPaul V McGraw
Mar 26, 2008·Journal of Cataract and Refractive Surgery·D T H Tan, Allan Fong
Jul 19, 2008·Current Biology : CB·Benjamin ThompsonRobert F Hess
Dec 26, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Daniella TerneyWalter Paulus
Mar 3, 2009·Vision Research·Dennis M Levi, Roger W Li
Sep 18, 2009·Journal of Vision·Pamela E JeterZhong-Lin Lu
May 11, 2010·Current Biology : CB·Tianmiao HuaZhong-Lin Lu
Oct 27, 2010·Vision Research·Dov Sagi
Nov 4, 2010·Experimental Brain Research·Antje KraftStephan A Brandt
Mar 31, 2011·Investigative Ophthalmology & Visual Science·Jingrong LiRobert F Hess
Oct 11, 2011·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Andrew T AstlePaul V McGraw
Oct 28, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Anna FertonaniCarlo Miniussi
Nov 29, 2011·Vision Research·Michael H HerzogHenning Sprekeler
Mar 1, 2012·Scientific Reports·U PolatDennis M Levi
Oct 11, 2012·Journal of Vision·David P McGovernJonathan W Peirce
Apr 9, 2013·Neuropsychologia·Megan A K PetersLadan Shams
May 4, 2013·Behavioural Brain Research·Hironori Kumano, Takanori Uka
May 15, 2013·Brain Stimulation·Simon ClavagnierRobert F Hess
Sep 17, 2013·The British Journal of Ophthalmology·Jingjing ZhaiJiahong Gao
Feb 20, 2014·Investigative Ophthalmology & Visual Science·Jun-Yun ZhangCong Yu
Jul 27, 2014·Attention, Perception & Psychophysics·Rebecca CamilleriGianluca Campana
Aug 1, 2014·Frontiers in Neural Circuits·Joyce BonaccorsiAlessandro Sale


Feb 19, 2016·Restorative Neurology and Neuroscience·Ulrich PalmSamar S Ayache
Apr 24, 2016·Social Cognitive and Affective Neuroscience·Martijn van KoningsbruggenClayton Hickey
Aug 29, 2016·Restorative Neurology and Neuroscience·Marcello ManigliaClara Casco
Dec 21, 2019·Neurorehabilitation and Neural Repair·Estelle RaffinFriedhelm Christoph Hummel
Jul 13, 2020·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Gianluca CampanaPaul V McGraw
Jan 14, 2017·Frontiers in Systems Neuroscience·Marcello ManigliaYves Trotter
Dec 31, 2019·Restorative Neurology and Neuroscience·Cecilia PerinCesare Giuseppe Cerri
May 7, 2016·Current Opinion in Ophthalmology·Aldo Vagge, Leonard B Nelson
Jan 1, 2017·Multisensory Research·Louise O'Hare
Jul 10, 2018·Scientific Reports·G MioniF Stablum
Mar 12, 2019·Restorative Neurology and Neuroscience·Qing HeChang-Bing Huang
Oct 6, 2020·Restorative Neurology and Neuroscience·Luca BattagliniClara Casco
Aug 15, 2018·Neuropsychologia·Florian HerpichLorella Battelli
Nov 2, 2020·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Sarah GarciaMichael A Eskenazi

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

KIF1A Associated Neurological Disorder

KIF1A associated neurological disorder (KAND) is a rare neurodegenerative condition caused by mutations in the KIF1A gene. KAND may present with a wide range and severity of symptoms including stiff or weak leg muscles, low muscle tone, a lack of muscle coordination and balance, and intellectual disability. Find the latest research on KAND here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Related Papers

Transactions of the American Ophthalmological Society
Daniel Durrie, Peter Shaw McMinn
Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
Po-Liang ChenDa-Wen Lu
Restorative Neurology and Neuroscience
Clara CascoAndrea Pavan
© 2021 Meta ULC. All rights reserved