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Improving access to endogenous DNA in ancient bones and teeth

bioRxiv

Feb 6, 2015

Peter de Barros DamgaardMorten E. Allentoft

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Abstract

Poor DNA preservation is the most limiting factor in ancient genomic research. In the vast majority of ancient bones and teeth, endogenous DNA molecules only represent a minor fraction of the whole DNA extract, rendering traditional shot-gun sequencing approaches cost-ineffective for wh...read more

Mentioned in this Paper

Skeletal Bone
Injection of Therapeutic Agent
Dental Cementum
Ancient DNA
Genome
Digestion
Research Study
Research
Edetic Acid
Biologic Preservation
18
1
2
Paper Details
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  • Improving access to endogenous DNA in ancient bones and teeth

    bioRxiv

    Feb 6, 2015

    Peter de Barros DamgaardMorten E. Allentoft

    PMID: 990014985

    DOI: 10.1101/014985

    Abstract

    Poor DNA preservation is the most limiting factor in ancient genomic research. In the vast majority of ancient bones and teeth, endogenous DNA molecules only represent a minor fraction of the whole DNA extract, rendering traditional shot-gun sequencing approaches cost-ineffective for wh...read more

    Mentioned in this Paper

    Skeletal Bone
    Injection of Therapeutic Agent
    Dental Cementum
    Ancient DNA
    Genome
    18
    1
    2
    Paper Details
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