Improving adherence to gout therapy: an expert review

Therapeutics and Clinical Risk Management
Fernando Perez-Ruiz, Giovambattista Desideri

Abstract

Gout is the most common form of inflammatory arthritis and is a considerable burden to patients and health care systems worldwide. Despite its clinical, economic, and social impact, patient persistence and adherence to prescribed urate-lowering therapies (ULT), ranging from 20% to 70%, is considered to be among the poorest of all chronic conditions. The majority of gout patients consequently receive suboptimal benefits of their prescribed pharmacotherapies. As gout is associated with several comorbidities along with an increased risk of premature mortality, achieving improved outcomes through adherence to ULT is crucial. Adherence to medication is complex and multidimensional and includes a combination of treatment-, patient-, and physician-related factors. This review explores the factors related to ULT adherence with the overall aim of helping health care providers better understand the barriers to adherence. Several interventions targeting pharmacists, nurses, and patients are being investigated to improve adherence. Furthermore, enhanced awareness and understanding of the need to treat-to-target in order to improve patient outcomes is needed among health care professionals. Greater understanding of the multidimensional natu...Continue Reading

Citations

May 31, 2019·Rheumatology International·Irvin J HuangAlison M Bays
May 1, 2019·Current Developments in Nutrition·Keith R Martin, Katie M Coles
Oct 29, 2020·Rheumatology and Therapy·Fernando Perez-RuizAustin G Stack

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BETA
pharmacotherapy

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CACTUS

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