Improving animal and human health through understanding liver fluke immunology

Parasite Immunology
D PiedrafitaH W Raadsma

Abstract

Sheep, goats and cattle represent the most numerous and economically important agricultural species worldwide used as sources for milk, fibre and red meat. In addition, in the developing world, these species often represent the sole asset base for small-holder livestock farmers and cattle/buffaloes often provide the majority of draught power for crop production. Production losses caused by helminth diseases of these animals are a major factor in extending the cycle of poverty in developing countries and a major food security issue for developed economies. Fasciola spp. are one of the most important zoonotic diseases with a global economic impact in livestock production systems and a poorly defined but direct effect on human health. Improvements in human and animal health will require a concerted research effort into the development of new accurate and simple diagnostic tests and increased vaccine and drug development against Fasciola infections. Here, the use of definitive natural host breeds with contrasting resistance to Fasciola infections is discussed as a resource to contrast parasite-host interactions and identify parasite immune evasion strategies. Such studies are likely to boost the discovery of new vaccine, drug and d...Continue Reading

Citations

Sep 14, 2010·Trends in Parasitology·David PiedrafitaEls Meeusen
Jun 23, 2015·Veterinary Parasitology·Collette BrittonEileen Devaney
Sep 19, 2015·Folia Parasitologica·Maria de Los Angeles Gutierrez-SanchezJorge Luis de la Rosa-Arana
Feb 7, 2015·Veterinary Parasitology·Verónica Molina-HernándezKrystyna Cwiklinski
Jul 11, 2013·Veterinary Immunology and Immunopathology·R ZafraA Martínez-Moreno
Jun 14, 2014·Veterinary Parasitology·Yris BloemhoffRíona Sayers
Sep 10, 2014·International Journal for Parasitology·Hayley ToetTerry W Spithill
May 31, 2016·Parasitology International·Timir TripathiBanchob Sripa
Aug 27, 2016·BioMed Research International·Abel Villa-ManceraJosé Zumaquero-Ríos
Jul 20, 2012·Journal of Community Health·Chanam LeeSamuel N Forjuoh
Apr 16, 2014·Scandinavian Journal of Medicine & Science in Sports·E A JaarsmaR Dekker
Mar 18, 2015·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ivelisse MartinAna M Espino
Jan 12, 2021·Frontiers in Veterinary Science·Shailesh ShresthaMike R Hutchings
Apr 4, 2021·International Journal of Molecular Sciences·Asahiro MorishitaTsutomu Masaki
Jul 3, 2021·Animals : an Open Access Journal From MDPI·Gemma ZernaTravis Beddoe
Aug 3, 2021·Frontiers in Veterinary Science·Theo de Waal, Khalid Mehmood

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Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

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