Improving Antibacterial Activity and Biocompatibility of Bioinspired Electrospinning Silk Fibroin Nanofibers Modified by Graphene Oxide

ACS Omega
Shu-Dong WangHong-Wu Chen

Abstract

In this article, the silk fibroin (SF)/graphene oxide (GO)-blended nanofibers with one bioinspired nanostructure are fabricated via electrospinning. The morphology, chemical structure, antibacterial activity, and biocompatibility of the blending nanofibers are investigated. The results indicate that GO plays an important role in preparing the distinctive bioinspired structure. The antibacterial activity and in vivo cell culture test demonstrate that blending of GO could improve the antibacterial activity and biocompatibility of SF nanofibers. The blended nanofibers developed in this study may have considerable potential for wound dressing applications.

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Citations

Oct 30, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Kun LiYubo Fan
Apr 21, 2018·Nanomaterials·Abdullah M Al-EniziAhmed A Elzatahry
Dec 27, 2018·Advanced Functional Materials·Yu WangShengjie Ling
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Aug 8, 2021·Nanomaterials·Honghai LiYanchuan Guo
Jan 20, 2021·ACS Biomaterials Science & Engineering·Suna FanYaopeng Zhang

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Methods Mentioned

BETA
scanning
X-ray
atomic force microscopy
AFM
confocal microscopy

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