Improving diagnostic accuracy in the transport of infants with suspected duct-dependent congenital heart disease

Journal of Paediatrics and Child Health
Neelam GuptaNeil Patel

Abstract

To identify factors that distinguish duct-dependent congenital heart disease (DDCHD) from non-DDCHD in newborn infants. A retrospective, cohort study. The Newborn Emergency Transport Service, Victoria (NETS) is a retrieval service for all inter-hospital neonatal transfers, and the Royal Children's Hospital, Melbourne (RCH) is a paediatric cardiac referral centre for the state of Victoria, Australia. All infants ≤10 days and ≥34 weeks gestation with suspected CHD and/or persistent pulmonary hypertension of the newborn (PPHN), transferred by NETS from non-tertiary neonatal units to RCH, over a 4-year period. Of 142 eligible infants, 81 had DDCHD and 61 had non-DDCHD, of whom 51 had PPHN. Diagnostic accuracy of DDCHD by the NETS team was 77%. Presence of a heart murmur, abnormal pulses, upper and lower limb blood pressure (BP) difference >10 mmHg, cardiomegaly, initial SpO2 of <92%, PaO2 <50 mmHg, and pre-post ductal SpO2 difference >10% were significantly associated with DDHCD on univariate analysis. No single clinical finding was significantly associated with DDCHD on multivariate analysis. Labile SpO2 , abnormal lung parenchyma, mean BP <40 mmHg, pH <7.25, lactate >5 and FiO2 >0.5 were significantly associated with non-DDCHD, b...Continue Reading

References

Nov 1, 1986·Journal of the American College of Cardiology·D A DanfordD G McNamara
Oct 1, 1983·The American Journal of Cardiology·L A LindayM A Engle
Dec 10, 1994·BMJ : British Medical Journal·H MontgomeryR M Marshall
Apr 2, 1999·Pediatrics·K S KuehlC Ferencz
Apr 26, 2001·Archives of Disease in Childhood. Fetal and Neonatal Edition·D J Penny, L S Shekerdemian
Aug 15, 2006·Archives of Disease in Childhood. Fetal and Neonatal Edition·Kathryn A Browning CarmoNadia Badawi
Aug 23, 2006·Archives of Disease in Childhood. Fetal and Neonatal Edition·L McGlone, L Jackson
Oct 19, 2006·Journal of Paediatrics and Child Health·Colleen ChewDaniel James Penny
Dec 10, 2008·Pediatrics·Garth D Meckler, Calvin Lowe
Oct 15, 2011·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Luc MertensUNKNOWN Association for European Pediatric Cardiologists (AEPC)
Dec 14, 2012·Archives of Disease in Childhood. Fetal and Neonatal Edition·Neelam GuptaNeil Patel

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Citations

Aug 11, 2020·Journal of Paediatrics and Child Health·Stephanie M BoydKathryn Browning Carmo

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