Improving drug adherence in osteoporosis: an update on more recent studies

Therapeutic Advances in Musculoskeletal Disease
Ayesha JaleelMaria I Danila

Abstract

Similar to other chronic diseases such as diabetes and hypertension, osteoporosis has struggled with suboptimal medication adherence, resulting in an increased risk of fractures and all-cause mortality. The goal of this narrative review was to summarize interventions to improve medication adherence in osteoporosis. Because past reviews of this topic covered published literature through 2013, we conducted our literature search to include the period between January 2012 and November 2017. We identified 10 studies evaluating healthcare system and patient interventions aimed at improving osteoporosis treatment adherence, including three fracture liaison service (FLS) programs, one pharmacist-delivered counseling program, and six patient-directed interventions consisting of three coaching or counseling programs and three interventions using reminder prompts. Four out of the six patient-directed interventions did not lead to significant improvements in outcomes, suggesting that patient-directed interventions may have limited success in this setting. The healthcare system interventions that evaluated FLS programs and pharmacist-directed tailored counseling were effective at improving medication adherence; however, the studies were not...Continue Reading

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Citations

Jun 15, 2019·The Journal of Experimental Medicine·Mi YangXiang-Hang Luo
Feb 6, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·G AdamiM I Danila
Nov 30, 2019·Journal of Primary Care & Community Health·Sarah Bou MalhamJulia P Dunn
Jun 1, 2021·International Journal of Rheumatic Diseases·Didier PoivretVéronique Noirez
Jun 20, 2021·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Li-Nien ChienDing-Cheng Chan
Aug 10, 2021·JBMR Plus·Nicole SagallaCathleen Colón-Emeric

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Methods Mentioned

BETA
x-ray

Software Mentioned

MeMO
Medication Monitoring and Optimization ( MeMO )

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