Improving GRADE evidence tables part 1: a randomized trial shows improved understanding of content in summary of findings tables with a new format

Journal of Clinical Epidemiology
Alonso Carrasco-LabraHolger Schünemann

Abstract

The current format of summary of findings (SoFs) tables for presenting effect estimates and associated quality of evidence improve understanding and assist users finding key information in systematic reviews. Users of SoF tables have demanded alternative formats to express findings from systematic reviews. We conducted a randomized controlled trial among systematic review users to compare the relative merits of a new format with the current formats of SoF tables regarding understanding, accessibility of information, satisfaction, and preference. Our primary goal was to show that the new format is not inferior to the current format. Of 390 potentially eligible subjects, 290 were randomized. Of seven items testing understanding, three showed similar results, two showed small differences favoring the new format, and two (understanding risk difference and quality of the evidence associated with a treatment effect) showed large differences favoring the new format [63% (95% confidence interval {CI}: 55, 71) and 62% (95% CI: 52, 71) more correct answers, respectively]. Respondents rated information in the alternative format as more accessible overall and preferred the new format over the current format. While providing at least simila...Continue Reading

References

Mar 9, 2006·JAMA : the Journal of the American Medical Association·Gilda PiaggioUNKNOWN CONSORT Group
Apr 26, 2008·BMJ : British Medical Journal·Gordon H GuyattUNKNOWN GRADE Working Group
May 6, 2008·BMJ : British Medical Journal·Gordon H GuyattUNKNOWN GRADE Working Group
May 10, 2008·BMJ : British Medical Journal·Gordon H GuyattUNKNOWN GRADE Working Group
May 24, 2008·BMJ : British Medical Journal·Gordon H GuyattUNKNOWN GRADE Working Group
Aug 2, 2008·BMJ : British Medical Journal·Roman JaeschkeUNKNOWN GRADE Working Group
May 4, 2010·Journal of Clinical Epidemiology·Sarah E RosenbaumAndrew D Oxman
Jul 21, 2010·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Claire GlentonHelen Dilkes
Nov 19, 2011·Population Health Management·Nathan D ShippeeM Hassan Murad
May 23, 2012·Journal of Clinical Epidemiology·Gordon H GuyattHolger J Schünemann
Nov 3, 2012·Journal of Clinical Epidemiology·Gordon H GuyattHolger J Schunemann
Dec 27, 2012·JAMA : the Journal of the American Medical Association·Gilda PiaggioUNKNOWN CONSORT Group

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Citations

Jan 23, 2016·Journal of Clinical Epidemiology·Miranda LangendamHolger J Schünemann
May 13, 2017·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Reed A C Siemieniuk, Gordon H Guyatt
Feb 22, 2017·Journal of Clinical Epidemiology·P Alonso-CoelloG H Guyatt
Aug 2, 2018·Journal of Evaluation in Clinical Practice·Mathew Mercuri, Amiram Gafni
Mar 15, 2019·JBI Database of Systematic Reviews and Implementation Reports·Holger J SchünemannJan L Brozek
May 14, 2019·Orthodontics & Craniofacial Research·Thomas TasiosAnna-Bettina Haidich
Jan 10, 2019·Journal of Clinical Periodontology·Nadja NaenniChristoph H F Hämmerle
Sep 8, 2020·BMC Medical Research Methodology·Lawrence MbuagbawLehana Thabane
Sep 24, 2020·Journal of Clinical Medicine·Golnar HavakeshianSpyridon N Papageorgiou
Jun 7, 2020·Health and Quality of Life Outcomes·Tejan BaldehHolger J Schünemann
Nov 24, 2019·European Journal of Orthodontics·Spyridon N PapageorgiouTheodore Eliades
Oct 30, 2020·F1000Research·Marta RoquéJavier Zamora
Oct 29, 2020·Climacteric : the Journal of the International Menopause Society·P R E S NollI C E Sorpreso
Nov 13, 2020·The Cochrane Database of Systematic Reviews·Filipe B RodriguesJoão Costa
Nov 20, 2020·The Cochrane Database of Systematic Reviews·Gonçalo S DuarteJoão Costa
Nov 2, 2020·Journal of Clinical Epidemiology·Timothy Hugh BarkerZachary Munn
Mar 20, 2021·BMC Pulmonary Medicine·Ioulianos ApessosPaschalis Steiropoulos
Apr 15, 2021·The Cochrane Database of Systematic Reviews·Filipe B RodriguesJoão Costa
Nov 7, 2019·Complementary Therapies in Clinical Practice·Carolina Rodrigues MendonçaJalsi Tacon Arruda

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