Improving Long-Term Outcomes After Extracorporeal Membrane Oxygenation: From Observational Follow-Up Programs Toward Risk Stratification

Frontiers in Pediatrics
Hanneke IJsselstijnArno F J van Heijst

Abstract

Since the introduction of extracorporeal membrane oxygenation (ECMO), more neonates and children with cardiorespiratory failure survive. Interest has therefore shifted from reduction of mortality toward evaluation of long-term outcomes and prevention of morbidity. This review addresses the changes in ECMO population and the ECMO-treatment that may affect long-term outcomes, the diagnostic modalities to evaluate neurological morbidities and their contributions to prognostication of long-term outcomes. Most follow-up data have only become available from observational follow-up programs in neonatal ECMO-survivors. The main topics are discussed in this review. Recommendations for long-term follow up depend on the presence of neurological comorbidity, the nature and extent of the underlying disease, and the indication for ECMO. Follow up should preferably be offered as standard of care, and in an interdisciplinary, structured and standardized way. This permits evaluation of outcome data and effect of interventions. We propose a standardized approach and recommend that multiple domains should be evaluated during long-term follow up of neonates and children who needed extracorporeal life support.

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Citations

Feb 28, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Jo WrayAparna Hoskote
May 13, 2019·Pediatric Cardiology·Anjali SadhwaniRavi R Thiagarajan
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Aug 24, 2019·Frontiers in Pediatrics·Neysan Rafat, Thomas Schaible
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Nov 3, 2020·Journal of Pediatric Surgery·Amy E LawrencePeter C Minneci
Mar 4, 2021·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Heidi J Dalton, Sandra Buttram
Oct 16, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Giorgio CaturegliLiam L Chen
Jul 30, 2021·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Hanneke IjsselstijnAparna Hoskote
Apr 29, 2021·AJR. American Journal of Roentgenology·Judy H Squires, M Beth McCarville

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Methods Mentioned

BETA
Sedation
infrared spectroscopy
imaging techniques
imaging technique
infrared spectrophotometry

Software Mentioned

ELSO
CUS
Cogmed

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