Improving Nutritional and Functional Quality by Genome Editing of Crops: Status and Perspectives

Frontiers in Plant Science
Hyung-Keun Ku, Sun-Hwa Ha

Abstract

Genome-editing tools including meganucleases, zinc finger nucleases, transcription activator-like effector nucleases and clustered regularly interspaced short palindromic repeats (CRISPR) system have been applied to improve the quality of staple, oilseed, and horticultural crops with great accuracy and efficiency compared to conventional breeding. In particular, the CRISPR method has proven to be a feasible, cost-effective and versatile tool allowing precise and efficient editing of plant genomes in recent years, showing great potential in crop improvement. Until now, various genome-edited crops with enhanced commercial value have been developed by not only global companies but also small laboratories in universities, suggesting low entry barriers with respect to manpower and capital. In this study, we review the current applications of genome editing technologies to improve the nutritional and functional quality and preferred traits of various crops. Combining this rapidly advancing genome-editing technology and conventional breeding will greatly extend the potential of genome-edited crops and their commercialization.

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Citations

Feb 16, 2021·Journal of Experimental Botany·Ying ChenHannes Vanhaeren
Apr 4, 2021·International Journal of Molecular Sciences·Monika HalatRafal Baranski
May 31, 2021·Transgenic Research·Stuart J SmythWayne Parrott

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Methods Mentioned

BETA
genetic modification
SGA
transfection
transgenic
targeted mutations
genotyping

Software Mentioned

Simplot

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