Improving optical contact for functional near‑infrared brain spectroscopy and imaging with brush optodes.

Biomedical Optics Express
Bilal KhanGeorge Alexandrakis

Abstract

A novel brush optode was designed and demonstrated to overcome poor optical contact with the scalp that can occur during functional near infrared spectroscopy (fNIRS) and imaging due to light obstruction by hair. The brush optodes were implemented as an attachment to existing commercial flat-faced (conventional) fiber bundle optodes. The goal was that the brush optodes would thread through hair and improve optical contact on subjects with dense hair. Simulations and experiments were performed to assess the magnitude of these improvements. FNIRS measurements on 17 subjects with varying hair colors (blonde, brown, and black) and hair densities (0-2.96 hairs/mm(2)) were performed during a finger tapping protocol for both flat and brush optodes. In addition to reaching a study success rate of almost 100% when using the brush optode extensions, the measurement setup times were reduced by a factor of three. Furthermore, the brush optodes enabled improvements in the activation signal-to-noise ratio (SNR) by up to a factor of ten as well as significant (p < 0.05) increases in the detected area of activation (dAoA). The measured improvements in SNR were matched by Monte Carlo (MC) simulations of photon propagation through scalp and hair...Continue Reading

References

Oct 1, 1994·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·R C HaskellB J Tromberg
Apr 1, 1965·The Journal of Investigative Dermatology·J M BARMANV PECORARO
Oct 22, 2003·NeuroImage·Christian F BeckmannStephen M Smith
May 13, 2005·IEEE Transactions on Bio-medical Engineering·Meltem IzzetogluBanu Onaral
Aug 12, 2005·Optics Letters·Ben BrooksbySteven P Poplack
Dec 20, 2005·Cardiovascular Research·Claude Julien
Jun 23, 2006·Physics in Medicine and Biology·Gerd Muehllehner, Joel S Karp
Sep 9, 2006·NeuroImage·Archana K Singh, Ippeita Dan
Nov 10, 2006·Journal of Biomedical Optics·Maria Angela FranceschiniDavid A Boas
Dec 30, 2008·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Kaiming LiTianming Liu
Feb 21, 2009·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Xiaoxiao BaiBin He
Apr 14, 2009·Journal of Alzheimer's Disease : JAD·David H BurnsHyman M Schipper
May 2, 2009·Journal of Biomedical Optics·David J CucciaBruce J Tromberg
May 2, 2009·Journal of Biomedical Optics·Aleksey KharinNatallia Uzunbajakava
Jul 8, 2009·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Adam Gibson, Hamid Dehghani
Jul 21, 2009·Cephalalgia : an International Journal of Headache·H W SchytzM Ashina
Aug 19, 2009·Optics Express·Sheng-Hao TsengNikiforos Kollias
Oct 8, 2009·Physics in Medicine and Biology·F AbdelnourT J Huppert
May 13, 2010·Journal of Biomedical Optics·Steve M LiaoJoseph P Culver
Jun 10, 2010·Physics in Medicine and Biology·F Orihuela-EspinaG Z Yang
Nov 13, 2010·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Francisco JimenezEnrique Poblet
Jan 5, 2011·Journal of Biomedical Optics·Andrei V MedvedevJohn Vanmeter
Sep 8, 2011·Journal of Biomedical Optics·Quan ZhangGary E Strangman

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Citations

Sep 30, 2015·Biomedical Optics Express·Robert FrancisDuncan MacFarlane
Jun 1, 2014·Journal of Neuroscience Methods·Simone Cutini, Sabrina Brigadoi
Jul 26, 2016·Biomedical Optics Express·Takeaki ShimokawaOkito Yamashita
Nov 2, 2014·Journal of Innovative Optical Health Sciences·Meryem A YücelDavid A Boas
Dec 7, 2016·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Fenghua TianLakshmi Raman
May 1, 2020·Frontiers in Human Neuroscience·Laurien Nagels-CouneBettina Sorger
Jan 27, 2019·Journal of Neuroengineering and Rehabilitation·Won-Seok KimNam-Jong Paik
Sep 27, 2018·Frontiers in Human Neuroscience·Joanne L ParkDavid I Donaldson

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Methods Mentioned

BETA
infrared spectroscopy

Software Mentioned

HomER
SAS
FRED
MATLAB

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