Improving self-report measures of medication non-adherence using a cheating detection extension of the randomised-response-technique

Statistical Methods in Medical Research
Martin OstapczukMorten Moshagen

Abstract

Medication non-adherence is a serious problem for medical research and clinical practice. Self-reports are only moderately valid, and objective methods are cumbersome and expensive to administer. We sought to improve self-reports of medication non-adherence using a cheating detection extension of the randomised-response-technique (RRT). This RRT variant encourages more honest responses by offering interviewees a higher degree of anonymity while simultaneously allowing us to estimate the proportion of respondents disobeying the RRT instructions. The 597 patients were asked to report their lifetime prevalence of medication non-adherence under one of two different questioning procedures, direct questioning or randomised-response. When questioned directly, only 20.9% of patients admitted to intentional medication non-adherent behaviour, as opposed to 32.7% of patients under RRT conditions. Additionally, the cheating detection extension revealed a significant proportion of patients (47.1%) disobeying the instructions in the RRT condition. Assuming that either none or all of them were non-adherent, a lower and upper bound of 32.7% and 79.8%, respectively, could be estimated for the lifetime prevalence of non-adherent behaviour. The r...Continue Reading

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Citations

Aug 23, 2011·Behavior Research Methods·Morten MoshagenEdgar Erdfelder
Jun 12, 2013·Statistics in Medicine·J-P FoxJ van der Palen
Sep 16, 2016·Behavior Research Methods·Adrian HoffmannJochen Musch
May 13, 2018·Conservation Biology : the Journal of the Society for Conservation Biology·Charlotte H ChangXingli Giam
Sep 17, 2017·Behavior Research Methods·Daniel W HeckMorten Moshagen
May 28, 2019·Statistical Methods in Medical Research·Amanda My ChuAgnes Tiwari
Aug 19, 2021·Biological Conservation·Harriet IbbettFreya A V St John

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