Improving survival in adenocarcinoma of the duodenum

American Journal of Surgery
D R JoestingL H Weiland

Abstract

The records of 104 patients with primary adenocarcinoma of the duodenum were reviewed. All patients were followed up to the date of this report, 91 for at least 5 years. Melena was an ominous preoperative finding. Survival was directly related to nodal status, the grade of the lesion, and the ability of the surgeon to minimize or eliminate operative mortality. Fifty percent of the lesions were resectable for cure, and the 5 year survival rate for patients with resectable lesions was 46 percent. All eight patients treated with segmental resections for lesions in the third and fourth portions of the duodenum survived at least 5 years. These data are a great improvement over those in previous reports and suggest that this disease may be much more treatable than previously believed.

References

Dec 1, 1975·The British Journal of Surgery·K SatakeH Kinoshita
Nov 1, 1973·The British Journal of Surgery·S Sakker, C C Ware
Mar 12, 1973·JAMA : the Journal of the American Medical Association·P L SchnurE G Harrison

Citations

Jul 1, 1992·Journal of Surgical Oncology·H KusumotoK Sugimachi
Jan 1, 1995·Surgery Today·S YildirimN Ozdemir
Nov 1, 1991·Digestive Diseases and Sciences·T OhkusaH Fujimoto
Oct 1, 1988·World Journal of Surgery·E C LaiR K Tompkins
Jan 1, 1991·Gastrointestinal Radiology·W Cwikiel, A Andrén-Sandberg
Jan 18, 2007·Digestive Diseases and Sciences·Yoshiki KatakuraFumio Itoh
Feb 22, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Edwin O OnkendiFlorencia G Que
Jan 5, 2001·The Surgical Clinics of North America·J E GervasoniB Cady
Jul 31, 2013·Nature Reviews. Clinical Oncology·Kanwal Raghav, Michael J Overman
Jul 14, 2001·ANZ Journal of Surgery·R R HutchinsS J Snooks
Jan 23, 1999·Journal of Clinical Gastroenterology·Y TanakaY Esaki
Jun 11, 2011·American Journal of Clinical Oncology·Kyubo KimSung W Ha
Oct 1, 1987·Postgraduate Medical Journal·A Carragher, C Russell
Feb 1, 1993·Postgraduate Medical Journal·N KaminskiR Eliakim
Jun 1, 1995·Postgraduate Medical Journal·O A AdedejiM Garcia-Zarco
Oct 27, 2011·International Surgery·Hiroshi KawahiraHisahiro Matsubara
Aug 28, 2014·Annals of Surgical Oncology·Jordan M CloydGeorge A Poultsides
Aug 1, 1995·Journal of Gastroenterology·T SatoT Matsushiro
Aug 1, 2008·World Journal of Surgery·Hyung Geun LeeDong Wook Choi
Apr 1, 1986·Gastrointestinal Endoscopy·E FriedmanL Cummins
Dec 1, 1993·American Journal of Surgery·R DelcoreA S Hermreck
Mar 29, 2000·American Journal of Surgery·I G KaklamanosA S Livingstone
Dec 1, 1987·American Journal of Surgery·M S Lea, L H Stahlgren
Aug 11, 2007·International Journal of Radiation Oncology, Biology, Physics·Chris R KelseyBrian G Czito
May 6, 2015·Surgical Oncology·T BuchbjergM B Mortensen
Sep 1, 1981·American Journal of Surgery·J A van HeerdenD M Ilstrup
Jan 1, 1988·Upsala Journal of Medical Sciences·G Jacobson, C E Nordgren
Mar 30, 2016·World Journal of Gastrointestinal Surgery·Jordan M CloydBrendan C Visser
Oct 1, 1994·The British Journal of Surgery·D M Scott-Coombes, R C Williamson
Jan 1, 1985·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·E de JuanR Machemer
Jul 20, 2007·The Cochrane Database of Systematic Reviews·N Singhal, D Singhal
Jan 1, 1994·Annals of Surgical Oncology·G BarnesS A Curley
Apr 1, 1985·Scottish Medical Journal·A MackayJ D Matthews
Oct 1, 1994·Scandinavian Journal of Gastroenterology·C J Tsai

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Nodding Syndrome

Nodding Syndrome is a neurological and epileptiform disorder characterized by psychomotor, mental, and growth retardation. Discover the latest research on Nodding Syndrome here.

LRRK2 & Microtubules

Mutations in the LRRK2 gene are risk-factors for developing Parkinson’s disease (PD). LRRK2 mutations in PD have been shown to enhance its association with microtubules. Here is the latest research.