Improving the Accuracy of Cardiovascular Component of the Sequential Organ Failure Assessment Score

Critical Care Medicine
Hemang YadavRodrigo Cartin-Ceba

Abstract

The Sequential Organ Failure Assessment score is an attractive risk prediction model because of its simplicity and graded assessment of morbidity and mortality. Due to changes in clinical practice over time, the cardiovascular component of the Sequential Organ Failure Assessment score no longer accurately reflects current clinical practice. To address this limitation, we developed and validated a modified cardiovascular component of the Sequential Organ Failure Assessment score that takes into account all vasoactive agents used in current clinical practice, uses shock index as a substitute for mean arterial pressure, and incorporates serum lactate as a biomarker for shock states. Retrospective cohort. Mayo Clinic, Rochester, MN. Adult patients admitted to one of six ICUs. None. Score performance was assessed via area under the receiver operator characteristic curve. A total of 16,386 ICU admissions were included: 9,204 in the derivation cohort and 7,182 in the validation cohort. area under the receiver operator characteristic curve was significantly higher for modified cardiovascular component of the Sequential Organ Failure Assessment score than for cardiovascular component of the Sequential Organ Failure Assessment for in-ICU...Continue Reading

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Citations

Feb 21, 2018·Therapeutic Hypothermia and Temperature Management·Julien Duranceau, Michael Mayette
Nov 24, 2018·Annals of Intensive Care·Saraschandra VallabhajosyulaVivek N Iyer
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Jul 13, 2021·The Open Respiratory Medicine Journal·Rahul KashyapSalim Surani

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