Improving the accuracy of the diagnosis of schizophrenia by means of virtual reality

The American Journal of Psychiatry
Anna SorkinAvi Peled

Abstract

The authors' goal was to improve the diagnosis of schizophrenia by using virtual reality technology to build a complex, multimodal environment in which cognitive functions can be studied (and measured) in parallel. The authors studied sensory integration within working memory by means of computer navigation through a virtual maze. The simulated journey consisted of a series of rooms, each of which included three doors. Each door was characterized by three features (color, shape, and sound), and a single combination of features--the door-opening rule--was correct. Subjects had to learn the rule and use it. The participants were 39 schizophrenic patients and 21 healthy comparison subjects. Upon completion, each subject was assigned a performance profile, including various error scores, response time, navigation ability, and strategy. A classification procedure based on the subjects' performance profile correctly predicted 85% of the schizophrenic patients (and all of the comparison subjects). Several performance variables showed significant correlations with scores on a standard diagnostic measure (Positive and Negative Syndrome Scale), suggesting potential use of these measurements for the diagnosis of schizophrenia. On the othe...Continue Reading

Citations

Apr 1, 2008·Schizophrenia Bulletin·Daniel Freeman
Aug 19, 2010·Current Opinion in Psychiatry·Alissa WestphalRobyn Attoe
Sep 7, 2014·Schizophrenia Bulletin·Wim VelingMark van der Gaag
Jul 15, 2015·Psychiatry Research·Sri Mahavir AgarwalGanesan Venkatasubramanian
Mar 11, 2016·Schizophrenia Research·Kathryn E GreenwoodTil Wykes
Mar 9, 2011·Clinical Psychology Review·Bonnie A Clough, Leanne M Casey
Jun 20, 2017·JBI Database of Systematic Reviews and Implementation Reports·Susan MaioccoMichelle Lieggi
Jul 19, 2016·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·E BekeleN Sarkar
Jul 7, 2007·Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists·Jeffrey Looi, Beverley Raphael
Sep 21, 2017·Frontiers in Psychiatry·Martine J van BennekomDamiaan Denys

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