Improving the biodegradability in seawater test (OECD 306)

The Science of the Total Environment
Amelie OttRussell J Davenport

Abstract

Growth and extensive urbanisation of the human population has been accompanied by increased manufacture and use of chemical compounds. To classify the fate and behaviour of these compounds in the environment, a series of international standardised biodegradation screening tests (BSTs) were developed over 30 years ago. In recent years, regulatory emphasis (e.g. REACH) has shifted from measuring biodegradation towards prioritisations based on chemical persistence. In their current guise, BSTs are ineffective as screens for persistence. The marine BST OECD 306 in particular is prone to high levels of variation and produces a large number of fails, many of which can be considered false negatives. An ECETOC funded two-day workshop of academia, industry and regulatory bodies was held in 2015 to discuss improvements to the marine BSTs based on previous research findings from the Cefic LRI ECO11 project and other foregoing studies. During this workshop, methodological improvements to the OECD 306 test were discussed, in addition to clarifying guidance on testing and interpretation of results obtained from marine BSTs (such as pass criteria, lag phases, freshwater read across and complex substances). Methodologically: (i) increasing bac...Continue Reading

Citations

Jul 14, 2019·Ecotoxicology and Environmental Safety·Baptiste A J PoursatJohn R Parsons
Apr 30, 2021·Integrated Environmental Assessment and Management·Graham WhaleAndreas Schaeffer
Jun 18, 2021·Journal of Pesticide Science·Saki TakekoshiAkira Tachibana
Mar 13, 2020·Environmental Science & Technology·Amelie OttRussell J Davenport
Nov 18, 2021·Environmental Science & Technology·Emily B FranklinAllen H Goldstein
Nov 4, 2021·Integrated Environmental Assessment and Management·Aaron D RedmanNeil Wang

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